Statistical analysis
Statistical analysis was performed using IBM SPSS Statistics for Windows, Version 23.0 (IBM Corp., Armonk, NY). The normality assumptions were controlled by the Shapiro–Wilk test. Descriptive analyses were presented using mean±SD (range), median (range), or n (%), where appropriate. Categorical data were analyzed by Pearson chi-square or Fisher’s Exact test. Mann–Whitney U test and Student’s t-test were used for the analysis of non-normally and normally distributed numerical data, respectively. A p-value of less than 0.05 was considered statistically significant.