References
1. Osler W. The Principles and Practice of Medicine.  1st ed. NY: D. Appleton and Company; 1892; 497–501.
2. Holgate ST. A brief history of asthma and its mechanisms to modern concepts of disease pathogenesis. Allergy, asthma & immunology research . 2010; 2 : 165-71.
3. Asher MI, Montefort S, Bjorksten B, et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet . 2006;368 : 733-43.
4. Garcia-Serna AM, Martin-Orozco E, Jimenez-Guerrero P, et al.Cytokine profiles in cord blood in relation to prenatal traffic-related air pollution: The NELA cohort. Pediatr Allergy Immunol . 2022;33 : e13732.
5. Pesce G, Sese L, Calciano L, et al. Foetal exposure to heavy metals and risk of atopic diseases in early childhood. Pediatr Allergy Immunol . 2021; 32 : 242-50.
6. Baek HS, Won HY, Kim JH, et al. Association of phthalate exposure and airway dysfunction with mediation by serum periostin.Pediatr Allergy Immunol . 2021; 32 : 1681-90.
7. Theodorou J, Nowak E, Bock A, et al. Mitogen-activated protein kinase signaling in childhood asthma development and environment-mediated protection. Pediatr Allergy Immunol . 2022;33 : e13657.
8. Haahtela T. Biodiversity for resilience-What is needed for allergic children. Pediatr Allergy Immunol . 2022; 33 : e13779.
9. Grant TL, Wood RA. The influence of urban exposures and residence on childhood asthma. Pediatr Allergy Immunol . 2022; 33 : e13784.
10. Hernandez-Pacheco N, Kere M, Melen E. Gene-environment interactions in childhood asthma revisited; expanding the interaction concept.Pediatr Allergy Immunol . 2022; 33 : e13780.
11. Frei R, Heye K, Roduit C. Environmental influences on childhood allergies and asthma – Farm effect. Pediatr Allergy Immunol . 2022; 33 : e13807
12. Paciencia I, Cavaleiro Rufo J, Moreira A. Environmental inequality: air pollution and asthma in children. Pediatr Allergy Immunol . 2022; 33 : e13818