References
- Abdelaal, M., le Roux, C. W., & Docherty, N. G. (2017). Morbidity and
mortality associated with obesity. Annals of Translational
Medicine . https://doi.org/10.21037/atm.2017.03.107
- Ahn, J., Lee, H., Im, S. W., Jung, C. H., & Ha, T. Y. (2014). Allyl
isothiocyanate ameliorates insulin resistance through the regulation
of mitochondrial function. Journal of Nutritional Biochemistry ,25 (10), 1026–1034.
https://doi.org/10.1016/j.jnutbio.2014.05.006
- Alenmyr, L., Herrmann, A., Högestätt, E. D., Greiff, L., & Zygmunt,
P. M. (2011). TRPV1 and TRPA1 stimulation induces MUC5B secretion in
the human nasal airway in vivo. Clinical Physiology and
Functional Imaging . https://doi.org/10.1111/j.1475-097X.2011.01039.x
- Alpizar, Y. A., Gees, M., Sanchez, A., Apetrei, A., Voets, T., Nilius,
B., & Talavera, K. (2013). Bimodal effects of cinnamaldehyde and
camphor on mouse TRPA1. Pflugers Archiv European Journal of
Physiology . https://doi.org/10.1007/s00424-012-1204-x
- Anand, P., Murali, K. Y., Tandon, V., Murthy, P. S., & Chandra, R.
(2010). Insulinotropic effect of cinnamaldehyde on transcriptional
regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and
GLUT4 translocation in experimental diabetic rats.Chemico-Biological Interactions , 186 (1), 72–81.
https://doi.org/10.1016/j.cbi.2010.03.044
- Arenas, O. M., Zaharieva, E. E., Para, A., Vásquez-Doorman, C.,
Petersen, C. P., & Gallio, M. (2017). Activation of planarian TRPA1
by reactive oxygen species reveals a conserved mechanism for animal
nociception. Nature Neuroscience .
https://doi.org/10.1038/s41593-017-0005-0
- Atoyan, R., Shander, D., & Botchkareva, N. V. (2009). Non-neuronal
expression of transient receptor potential type A1 (TRPA1) in human
skin. Journal of Investigative Dermatology .
https://doi.org/10.1038/jid.2009.58
- Autzen, H. E., Myasnikov, A. G., Campbell, M. G., Asarnow, D., Julius,
D., & Cheng, Y. (2018). Structure of the human TRPM4 ion channel in a
lipid nanodisc. Science .
https://doi.org/10.1126/science.aar4510
- Babes, A., Fischer, M. J. M., Filipovic, M., Engel, M. A., Flonta, M.
L., & Reeh, P. W. (2013). The anti-diabetic drug glibenclamide is an
agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion
channel. European Journal of Pharmacology .
https://doi.org/10.1016/j.ejphar.2013.02.018
- Babes, A., Sauer, S. K., Moparthi, L., Kichko, T. I., Neacsu, C.,
Namer, B., … Fischer, M. J. M. (2016). Photosensitization in
porphyrias and photodynamic therapy involves TRPA1 and TRPV1.Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.4268-15.2016
- Bahia, P. K., Parks, T. A., Stanford, K. R., Mitchell, D. A., Varma,
S., Stevens, S. M., & Taylor-Clark, T. E. (2016). The exceptionally
high reactivity of Cys 621 is critical for electrophilic activation of
the sensory nerve ion channel TRPA1. Journal of General
Physiology . https://doi.org/10.1085/jgp.201611581
- Bandell, M., Story, G. M., Hwang, S. W., Viswanath, V., Eid, S. R.,
Petrus, M. J., … Patapoutian, A. (2004). Noxious cold ion
channel TRPA1 is activated by pungent compounds and bradykinin.Neuron . https://doi.org/10.1016/S0896-6273(04)00150-3
- Barabas, M. E., Kossyreva, E. A., & Stucky, C. L. (2012). TRPA1 Is
Functionally Expressed Primarily by IB4-Binding, Non-Peptidergic Mouse
and Rat Sensory Neurons. PLoS ONE .
https://doi.org/10.1371/journal.pone.0047988
- Bautista, D. M., Jordt, S., Nikai, T., Tsuruda, P. R., Read, A. J.,
Poblete, J., … Julius, D. (2006). TRPA1 Mediates the
Inflammatory Actions of Environmental Irritants and Proalgesic Agents,
1269–1282. https://doi.org/10.1016/j.cell.2006.02.023
- Bautista, D. M., Movahed, P., Hinman, A., Axelsson, H. E., Sterner,
O., Högestätt, E. D., … Zygmunt, P. M. (2005). Pungent products
from garlic activate the sensory ion channel TRPA1. Proceedings
of the National Academy of Sciences of the United States of America .
https://doi.org/10.1073/pnas.0505356102
- Bayan, L., Koulivand, P. H., & Gorji, A. (2014). Garlic: a review of
potential therapeutic effects. Avicenna Journal of
Phytomedicine , 4 (1), 1–14.
https://doi.org/10.22038/ajp.2014.1741
- Bessac, B. F., & Jordt, S. E. (2008). Breathtaking TRP channels:
TRPA1 and TRPV1 in airway chemosensation and reflex control.Physiology . https://doi.org/10.1152/physiol.00026.2008
- Bianchi, B. R., Zhang, X. F., Reilly, R. M., Kym, P. R., Yao, B. B.,
& Chen, J. (2012). Species comparison and pharmacological
characterization of human, monkey, rat, and mouse TRPA1 channels.Journal of Pharmacology and Experimental Therapeutics .
https://doi.org/10.1124/jpet.111.189902
- Bishnoi, M., Khare, P., & Brown, L. (2018). Transient receptor
potential ( TRP ) channels : a metabolic TR ( i ) P to obesity
prevention and therapy, (i). https://doi.org/10.1111/obr.12703
- Blüher, M. (2019). Obesity: global epidemiology and pathogenesis.Nature Reviews Endocrinology , 15 (5), 288–298.
https://doi.org/10.1038/s41574-019-0176-8
- Boden, G. (2011). Obesity, insulin resistance and free fatty acids.Current Opinion in Endocrinology, Diabetes and Obesity .
https://doi.org/10.1097/MED.0b013e3283444b09
- Caceres, A. I., Brackmann, M., Elia, M. D., Bessac, B. F., Del Camino,
D., D’Amours, M., … Jordt, S. E. (2009). A sensory neuronal ion
channel essential for airway inflammation and hyperreactivity in
asthma. Proceedings of the National Academy of Sciences of the
United States of America . https://doi.org/10.1073/pnas.0900591106
- Camacho, S., Michlig, S., De Senarclens-Bezençon, C., Meylan, J.,
Meystre, J., Pezzoli, M., … Le Coutre, J. (2015). Anti-obesity
and anti-hyperglycemic effects of cinnamaldehyde via altered ghrelin
secretion and functional impact on food intake and gastric emptying.Scientific Reports . https://doi.org/10.1038/srep07919
- Cao, D. S., Zhong, L., Hsieh, T. han, Abooj, M., Bishnoi, M., Hughes,
L., & Premkumar, L. S. (2012). Expression of transient receptor
potential ankyrin 1 (TRPA1) and its role in insulin release from rat
pancreatic beta cells. PLoS ONE .
https://doi.org/10.1371/journal.pone.0038005
- Chepurny, O. G., Holz, G. G., Roe, M. W., & Leech, C. A. (2016).
GPR119 agonist AS1269574 activates TRPA1 cation channels to stimulate
GLP-1 secretion. Molecular Endocrinology , 30 (6),
614–629. https://doi.org/10.1210/me.2015-1306
- Chia, C. W., & Egan, J. M. (2020). Incretins in obesity and diabetes.Annals of the New York Academy of Sciences .
https://doi.org/10.1111/nyas.14211
- Cho, J. H., Jeong, M. Y., Choi, I. S., Lee, H. J., & Jang, I. S.
(2012). TRPA1-like channels enhance glycinergic transmission in
medullary dorsal horn neurons. Journal of Neurochemistry .
https://doi.org/10.1111/j.1471-4159.2012.07817.x
- Chung, G., Im, S. T., Kim, Y. H., Jung, S. J., Rhyu, M. R., & Oh, S.
B. (2014). Activation of transient receptor potential ankyrin 1 by
eugenol. Neuroscience .
https://doi.org/10.1016/j.neuroscience.2013.12.047
- Church, T., & Martin, C. K. (2018). The Obesity Epidemic: A
Consequence of Reduced Energy Expenditure and the Uncoupling of Energy
Intake? Obesity . https://doi.org/10.1002/oby.22072
- Cicero, S., & Herrup, K. (2005). Cyclin-dependent kinase 5 is
essential for neuronal cell cycle arrest and differentiation.Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.1773-05.2005
- Clapham, D. E., Montell, C., Schultz, G., & Julius, D. (2003).
International Union of Pharmacology. XLIII. Compendium of
Voltage-Gated Ion Channels: Transient Receptor Potential Channels.Pharmacological Reviews . https://doi.org/10.1124/pr.55.4.6
- Cordero-Morales, J. F., Gracheva, E. O., & Julius, D. (2012).
Cytoplasmic Ankyrin Repeats of Transient Receptor Potential A1 (TRPA1)
Dictate Sensitivity to Thermal and Chemical Stimuli. Biophysical
Journal . https://doi.org/10.1016/j.bpj.2011.11.151
- Corey, D. P., Garcia-Añoveros, J., Holt, J. R., Kwan, K. Y., Lin, S.
Y., Vollrath, M. A., … Zhang, D. S. (2004). TRPA1 is a
candidate for the mechanosensitive transduction channel of vertebrate
hair cells. Nature . https://doi.org/10.1038/nature03066
- Cvetkov, T. L., Huynh, K. W., Cohen, M. R., & Moiseenkova-Bell, V. Y.
(2011). Molecular architecture and subunit organization of TRPA1 ion
channel revealed by electron microscopy. Journal of Biological
Chemistry , 286 (44), 38168–38176.
https://doi.org/10.1074/jbc.M111.288993
- De Logu, F., Puma, S. L., Landini, L., Portelli, F., Innocenti, A., De
Araujo, D. S. M., … Nassini, R. (2019). Schwann cells
expressing nociceptive channel TRPA1 orchestrate ethanol-evoked
neuropathic pain in mice. Journal of Clinical Investigation .
https://doi.org/10.1172/JCI128022
- DeFalco, J., Steiger, D., Gustafson, A., Emerling, D. E., Kelly, M.
G., & Duncton, M. A. J. (2010). Oxime derivatives related to AP18:
Agonists and antagonists of the TRPA1 receptor. Bioorganic and
Medicinal Chemistry Letters .
https://doi.org/10.1016/j.bmcl.2009.10.113
- Diver, M. M., Cheng, Y., & Julius, D. (2019). Structural insights
into TRPM8 inhibition and desensitization. Science .
https://doi.org/10.1126/science.aax6672
- Doerner, J. F., Gisselmann, G., Hatt, H., & Wetzel, C. H. (2007).
Transient receptor potential channel A1 is directly gated by calcium
ions. Journal of Biological Chemistry .
https://doi.org/10.1074/jbc.M607849200
- Doihara, H., Nozawa, K., Kawabata-Shoda, E., Kojima, R., Yokoyama, T.,
& Ito, H. (2009). TRPA1 agonists delay gastric emptying in rats
through serotonergic pathways. Naunyn-Schmiedeberg’s Archives of
Pharmacology . https://doi.org/10.1007/s00210-009-0435-7
- Düfer, M., Hörth, K., Wagner, R., Schittenhelm, B., Prowald, S.,
Wagner, T. F. J., … Drews, G. (2012). Bile acids acutely
stimulate insulin secretion of mouse β-cells via farnesoid X receptor
activation and K ATP channel inhibition. Diabetes .
https://doi.org/10.2337/db11-0815
- El Karim, I. A., Linden, G. J., Curtis, T. M., About, I., McGahon, M.
K., Irwin, C. R., … Lundy, F. T. (2011). Human dental pulp
fibroblasts express the “cold-sensing” transient receptor potential
channels TRPA1 and TRPM8. Journal of Endodontics .
https://doi.org/10.1016/j.joen.2010.12.017
- Emery, E. C., Diakogiannaki, E., Gentry, C., Psichas, A., Habib, A.
M., Bevan, S., … Gribble, F. M. (2015). Stimulation of GLP-1
secretion downstream of the ligand-gated ion channel TRPA1.Diabetes . https://doi.org/10.2337/db14-0737
- Escalera, J., Von Hehn, C. A., Bessac, B. F., Sivula, M., & Jordt, S.
E. (2008). TRPA1 mediates the noxious effects of natural sesquiterpene
deterrents. Journal of Biological Chemistry .
https://doi.org/10.1074/jbc.M710280200
- Esser, N., Legrand-Poels, S., Piette, J., Scheen, A. J., & Paquot, N.
(2014). Inflammation as a link between obesity, metabolic syndrome and
type 2 diabetes. Diabetes Research and Clinical Practice .
https://doi.org/10.1016/j.diabres.2014.04.006
- Fernández-Verdejo, R., Marlatt, K. L., Ravussin, E., & Galgani, J. E.
(2019). Contribution of brown adipose tissue to human energy
metabolism. Molecular Aspects of Medicine .
https://doi.org/10.1016/j.mam.2019.07.003
- Finkelstein, E. A., Khavjou, O. A., Thompson, H., Trogdon, J. G., Pan,
L., Sherry, B., & Dietz, W. (2012). Obesity and severe obesity
forecasts through 2030. American Journal of Preventive
Medicine , 42 (6), 563–570.
https://doi.org/10.1016/j.amepre.2011.10.026
- Fothergill, L. J., Callaghan, B., Rivera, L. R., Lieu, T. M., Poole,
D. P., Cho, H. J., … Furness, J. B. (2016). Effects of food
components that activate TRPA1 receptors on mucosal ion transport in
the Mouse intestine. Nutrients .
https://doi.org/10.3390/nu8100623
- Friedrich, M. J. (2017). Global Obesity Epidemic Worsening.JAMA . https://doi.org/10.1001/jama.2017.10693
- Fujita, F., Moriyama, T., Higashi, T., Shima, A., & Tominaga, M.
(2007). Methyl p-hydroxybenzoate causes pain sensation through
activation of TRPA1 channels. British Journal of Pharmacology .
https://doi.org/10.1038/sj.bjp.0707219
- Fujita, Fumitaka, Uchida, K., Moriyama, T., Shima, A., Shibasaki, K.,
Inada, H., … Tominaga, M. (2008). Intracellular alkalization
causes pain sensation through activation of TRPA1 in mice.Journal of Clinical Investigation .
https://doi.org/10.1172/JCI35957
- Gaudet, R. (2008). A primer on ankyrin repeat function in TRP channels
and beyond. Molecular BioSystems .
https://doi.org/10.1039/b801481g
- Gershon, M. D., & Tack, J. (2007). The Serotonin Signaling System:
From Basic Understanding To Drug Development for Functional GI
Disorders. Gastroenterology .
https://doi.org/10.1053/j.gastro.2006.11.002
- Gracheva, E. O., Ingolia, N. T., Kelly, Y. M., Cordero-Morales, J. F.,
Hollopeter, G., Chesler, A. T., … Julius, D. (2010). Molecular
basis of infrared detection by snakes. Nature .
https://doi.org/10.1038/nature08943
- Hall, B. E., Prochazkova, M., Sapio, M. R., Minetos, P., Kurochkina,
N., Binukumar, B. K., … Kulkarni, A. B. (2018). Phosphorylation
of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent
Kinase 5 affects Chemo-nociception. Scientific Reports .
https://doi.org/10.1038/s41598-018-19532-6
- Hasan, R., Leeson-Payne, A. T. S., Jaggar, J. H., & Zhang, X. (2017).
Calmodulin is responsible for Ca2+-dependent regulation of TRPA1
Channels. Scientific Reports . https://doi.org/10.1038/srep45098
- Hata, T., Tazawa, S., Ohta, S., Rhyu, M. R., Misaka, T., & Ichihara,
K. (2012). Artepillin C, a Major Ingredient of Brazilian Propolis,
Induces a Pungent Taste by Activating TRPA1 Channels. PLoS ONE .
https://doi.org/10.1371/journal.pone.0048072
- Heilbronn, L., & Campbell, L. (2008). Adipose Tissue Macrophages, Low
Grade Inflammation and Insulin Resistance in Human Obesity.Current Pharmaceutical Design .
https://doi.org/10.2174/138161208784246153
- Hinman, A., Chuang, H. H., Bautista, D. M., & Julius, D. (2006). TRP
channel activation by reversible covalent modification.Proceedings of the National Academy of Sciences of the United
States of America . https://doi.org/10.1073/pnas.0609598103
- Hosseini, A., & Hosseinzadeh, H. (2015). A review on the effects of
Allium sativum (Garlic) in metabolic syndrome. Journal of
Endocrinological Investigation .
https://doi.org/10.1007/s40618-015-0313-8
- Hu, H., Tian, J., Zhu, Y., Wang, C., Xiao, R., Herz, J. M., …
Zhu, M. X. (2010). Activation of TRPA1 channels by fenamate
nonsteroidal anti-inflammatory drugs. Pflugers Archiv European
Journal of Physiology . https://doi.org/10.1007/s00424-009-0749-9
- Huang, C. L. (2004). The transient receptor potential superfamily of
ion channels. Journal of the American Society of Nephrology .
https://doi.org/10.1097/01.ASN.0000129115.69395.65
- Huang, Y., Winkler, P. A., Sun, W., Lü, W., & Du, J. (2018).
Architecture of the TRPM2 channel and its activation mechanism by
ADP-ribose and calcium. Nature .
https://doi.org/10.1038/s41586-018-0558-4
- Hynkova, A., Marsakova, L., Vaskova, J., & Vlachova, V. (2016).
N-terminal tetrapeptide T/SPLH motifs contribute to multimodal
activation of human TRPA1 channel. Scientific Reports ,6 (March), 1–16. https://doi.org/10.1038/srep28700
- Inoue, M., Fujita, T., Goto, M., & Kumamoto, E. (2012). Presynaptic
enhancement by eugenol of spontaneous excitatory transmission in rat
spinal substantia gelatinosa neurons is mediated by transient receptor
potential A1 channels. Neuroscience .
https://doi.org/10.1016/j.neuroscience.2012.02.040
- Iwasaki, Y., Tanabe, M., Kobata, K., & Watanabe, T. (2008). TRPA1
agonists - Allyl isothiocyanate and cinnamaldehyde - Induce adrenaline
secretion. Bioscience, Biotechnology and Biochemistry ,72 (10), 2608–2614. https://doi.org/10.1271/bbb.80289
- Jain, A., Brönneke, S., Kolbe, L., Stäb, F., Wenck, H., & Neufang, G.
(2011). TRP-channel-specific cutaneous eicosanoid release patterns.Pain . https://doi.org/10.1016/j.pain.2011.08.025
- Jaquemar, D., Schenker, T., & Trueb, B. (1999). An ankyrin-like
protein with transmembrane domains is specifically lost after
oncogenic transformation of human fibroblasts. Journal of
Biological Chemistry . https://doi.org/10.1074/jbc.274.11.7325
- Jiang, J., Emont, M. P., Jun, H., Qiao, X., Liao, J., Kim, D. il, &
Wu, J. (2017). Cinnamaldehyde induces fat cell-autonomous
thermogenesis and metabolic reprogramming. Metabolism: Clinical
and Experimental . https://doi.org/10.1016/j.metabol.2017.08.006
- Jordt, S. E., Bautista, D. M., Chuang, H. H., McKemy, D. D., Zygmunt,
P. M., Högestätt, E. D., … Julius, D. (2004). Mustard oils and
cannabinoids excite sensory nerve fibres through the TRP channel
ANKTM1. Nature . https://doi.org/10.1038/nature02282
- Kagawa, Y., Ozaki‑Masuzawa, Y., Hosono, T., & Seki, T. (2019). Garlic
oil suppresses high‑fat diet induced obesity in rats through the
upregulation of UCP‑1 and the enhancement of energy expenditure.Experimental and Therapeutic Medicine .
https://doi.org/10.3892/etm.2019.8386
- Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006). Mechanisms
linking obesity to insulin resistance and type 2 diabetes,444 (December). https://doi.org/10.1038/nature05482
- Kaimoto, T., Hatakeyama, Y., Takahashi, K., Imagawa, T., Tominaga, M.,
& Ohta, T. (2016). Involvement of transient receptor potential A1
channel in algesic and analgesic actions of the organic compound
limonene. European Journal of Pain (United Kingdom) .
https://doi.org/10.1002/ejp.840
- Kaji, I., Karaki, S. ichiro, & Kuwahara, A. (2011). Effects of
luminal thymol on epithelial transport in human and rat colon.American Journal of Physiology - Gastrointestinal and Liver
Physiology . https://doi.org/10.1152/ajpgi.00503.2010
- Kannler, M., Lüling, R., Yildirim, A. Ö., Gudermann, T., Steinritz,
D., & Dietrich, A. (2018). TRPA1 channels: expression in non-neuronal
murine lung tissues and dispensability for hyperoxia-induced alveolar
epithelial hyperplasia. Pflugers Archiv European Journal of
Physiology . https://doi.org/10.1007/s00424-018-2148-6
- Karashima, Y., Damann, N., Prenen, J., Talavera, K., Segal, A., Voets,
T., & Nilius, B. (2007). Bimodal action of menthol on the transient
receptor potential channel TRPA1. Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.2221-07.2007
- Khan, A., Safdar, M., Ali Khan, M. M., Khattak, K. N., & Anderson, R.
A. (2003). Cinnamon Improves Glucose and Lipids of People with Type 2
Diabetes. Diabetes Care .
https://doi.org/10.2337/diacare.26.12.3215
- Khare, P., Jagtap, S., Jain, Y., Baboota, R. K., Mangal, P., Boparai,
R. K., … Bishnoi, M. (2016). Cinnamaldehyde supplementation
prevents fasting-induced hyperphagia, lipid accumulation, and
inflammation in high-fat diet-fed mice. BioFactors .
https://doi.org/10.1002/biof.1265
- Kim, H. Y., Park, M., Kim, K., Lee, Y. M., & Rhyu, M. R. (2013).
Hesperetin stimulates cholecystokinin secretion in enteroendocrine
STC-1 cells. Biomolecules and Therapeutics , 21 (2),
121–125. https://doi.org/10.4062/biomolther.2012.077
- Kim, M. J., Son, H. J., Song, S. H., Jung, M., Kim, Y., & Rhyu, M. R.
(2013). The TRPA1 Agonist, Methyl Syringate Suppresses Food Intake and
Gastric Emptying. PLoS ONE , 8 (8), 1–6.
https://doi.org/10.1371/journal.pone.0071603
- Kim, S. H., & Choung, S. Y. (2010). Antihyperglycemic and
antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract
in C57BL/Ks db/db mice. Archives of Pharmacal Research .
https://doi.org/10.1007/s12272-010-0219-0
- Kim, Y. S., Son, J. Y., Kim, T. H., Paik, S. K., Dai, Y., Noguchi, K.,
… Bae, Y. C. (2010). Expression of transient receptor potential
ankyrin 1 (TRPA 1) in the rat trigeminal sensory afferents and spinal
dorsal horn. Journal of Comparative Neurology .
https://doi.org/10.1002/cne.22238
- Koch, M., Kreutz, S., Böttger, C., Grabiec, U., Ghadban, C., Korf, H.
W., & Dehghani, F. (2011). The cannabinoid WIN 55,212-2-mediated
protection of dentate gyrus granule cells is driven by CB 1 receptors
and modulated by TRPA1 and Ca v2.2 channels. Hippocampus .
https://doi.org/10.1002/hipo.20772
- Koizumi, K., Iwasaki, Y., Narukawa, M., Iitsuka, Y., Fukao, T., Seki,
T., … Watanabe, T. (2009). Diallyl sulfides in garlic activate
both TRPA1 and TRPV1. Biochemical and Biophysical Research
Communications . https://doi.org/10.1016/j.bbrc.2009.03.066
- Kong, X., Tu, Y., Li, B., Zhang, L., Feng, L., Wang, L., … Ma,
X. (2019). Roux-en-Y gastric bypass enhances insulin secretion in type
2 diabetes via FXR-mediated TRPA1 expression. Molecular
Metabolism , 29 (August), 1–11.
https://doi.org/10.1016/j.molmet.2019.08.009
- Kong, X., Tu, Y., Li, B., Zhang, L. L., Feng, L., Wang, L. L.,
… Derbenev, A. V. (2016). Roux-en-Y gastric bypass enhances
insulin secretion in type 2 diabetes via FXR-mediated TRPA1
expression. PLoS ONE , 29 (1), 1–11.
https://doi.org/10.1016/j.molmet.2019.08.009
- Kumar Pareek, T. (2012). Cdk5: An Emerging Kinase in Pain Signaling.Brain Disorders & Therapy .
https://doi.org/10.4172/2168-975x.s1-003
- La, J. H., Schwartz, E. S., & Gebhart, G. F. (2011). Differences in
the expression of transient receptor potential channel V1, transient
receptor potential channel A1 and mechanosensitive two pore-domain K +
channels between the lumbar splanchnic and pelvic nerve innervations
of mouse urinary bladder and co. Neuroscience , 186 ,
179–187. https://doi.org/10.1016/j.neuroscience.2011.04.049
- Lamprianou, S., Gysemans, C., Saab, J. B., Pontes, H., Mathieu, C., &
Meda, P. (2016). Glibenclamide prevents diabetes in NOD Mice.PLoS ONE . https://doi.org/10.1371/journal.pone.0168839
- Leamy, A. W., Shukla, P., McAlexander, M. A., Carr, M. J., & Ghatta,
S. (2011). Curcumin
((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione)
activates and desensitizes the nociceptor ion channel TRPA1.Neuroscience Letters .
https://doi.org/10.1016/j.neulet.2011.07.054
- Lean, M. E. J., & Malkova, D. (2016). Altered gut and adipose tissue
hormones in overweight and obese individuals: Cause or consequence.International Journal of Obesity .
https://doi.org/10.1038/ijo.2015.220
- Lee, S. P., Buber, M. T., Yang, Q., Cerne, R., Cortés, R. Y., Sprous,
D. G., & Bryant, R. W. (2008). Thymol and related alkyl phenols
activate the hTRPA1 channel. British Journal of Pharmacology .
https://doi.org/10.1038/bjp.2008.85
- Leffler, A., Lattrell, A., Kronewald, S., Niedermirtl, F., & Nau, C.
(2011). Activation of TRPA1 by membrane permeable local anesthetics.Molecular Pain . https://doi.org/10.1186/1744-8069-7-62
- Legrand, C., Merlini, J. M., de Senarclens-Bezençon, C., & Michlig,
S. (2020). New natural agonists of the transient receptor potential
Ankyrin 1 (TRPA1) channel. Scientific Reports , 10 (1),
11238. https://doi.org/10.1038/s41598-020-68013-2
- Lieder, B., Zaunschirm, M., Holik, A. K., Ley, J. P., Hans, J.,
Krammer, G. E., & Somoza, V. (2017). The alkamide trans-pellitorine
targets PPARγ via TRPV1 and TRPA1 to reduce lipid accumulation in
developing 3T3-L1 adipocytes. Frontiers in Pharmacology ,8 (MAY), 1–11. https://doi.org/10.3389/fphar.2017.00316
- Lim, G. E., & Brubaker, P. L. (2006). Glucagon-like peptide 1
secretion by the L-cell: The view from within. Diabetes .
https://doi.org/10.2337/db06-S020
- Loh, R. K. C., Kingwell, B. A., & Carey, A. L. (2017). Human brown
adipose tissue as a target for obesity management; beyond cold-induced
thermogenesis. Obesity Reviews .
https://doi.org/10.1111/obr.12584
- Ma, W., Chen, X., Cerne, R., Syed, S. K., Ficorilli, J. V., Cabrera,
O., … Efanov, A. M. (2019). Catechol estrogens stimulate
insulin secretion in pancreatic -cells via activation of the transient
receptor potential A1 (TRPA1) channel. Journal of Biological
Chemistry , 294 (8), 2935–2946.
https://doi.org/10.1074/jbc.RA118.005504
- Macpherson, L. J., Dubin, A. E., Evans, M. J., Marr, F., Schultz, P.
G., Cravatt, B. F., & Patapoutian, A. (2007). Noxious compounds
activate TRPA1 ion channels through covalent modification of
cysteines. Nature . https://doi.org/10.1038/nature05544
- Macpherson, L. J., Geierstanger, B. H., Viswanath, V., Bandell, M.,
Eid, S. R., Hwang, S., & Patapoutian, A. (2005). The Pungency of
Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin.Current Biology , 15 (10), 929–934.
https://doi.org/10.1016/j.cub.2005.04.018
- Manna, P., & Jain, S. K. (2015). Obesity, Oxidative Stress, Adipose
Tissue Dysfunction, and the Associated Health Risks: Causes and
Therapeutic Strategies. Metabolic Syndrome and Related
Disorders . https://doi.org/10.1089/met.2015.0095
- Matsushita, M., Yoneshiro, T., Aita, S., Kamiya, T., Kusaba, N.,
Yamaguchi, K., … Saito, M. (2015). Kaempferia parviflora
extract increases whole-body energy expenditure in humans: Roles of
brown adipose tissue. Journal of Nutritional Science and
Vitaminology , 61 (1), 79–83.
https://doi.org/10.3177/jnsv.61.79
- Matta, J. A., Cornett, P. M., Miyares, R. L., Abe, K., Sahibzada, N.,
& Ahern, G. P. (2008). General anesthetics activate a nociceptive ion
channel to enhance pain and inflammation. Proceedings of the
National Academy of Sciences of the United States of America .
https://doi.org/10.1073/pnas.0711038105
- May, D., Baastrup, J., Nientit, M. R., Binder, A., Schünke, M., Baron,
R., & Cascorbi, I. (2012). Differential expression and functionality
of TRPA1 protein genetic variants in conditions of thermal
stimulation. Journal of Biological Chemistry .
https://doi.org/10.1074/jbc.M112.341776
- Meents, J. E., Fischer, M. J. M., & McNaughton, P. A. (2016).
Agonist-induced sensitisation of the irritant receptor ion channel
TRPA1. Journal of Physiology . https://doi.org/10.1113/JP272237
- Meng, J., Wang, J., Steinhoff, M., & Dolly, J. O. (2016). TNFα
induces co-trafficking of TRPV1/TRPA1 in VAMP1-containing vesicles to
the plasmalemma via Munc18-1/syntaxin1/SNAP-25 mediated fusion.Scientific Reports , 6 (May 2015), 1–15.
https://doi.org/10.1038/srep21226
- Michlig, S., Merlini, J. M., Beaumont, M., Ledda, M., Tavenard, A.,
Mukherjee, R., … Le Coutre, J. (2016). Effects of TRP channel
agonist ingestion on metabolism and autonomic nervous system in a
randomized clinical trial of healthy subjects. Scientific
Reports . https://doi.org/10.1038/srep20795
- Motter, A. L., & Ahern, G. P. (2012). TRPA1 is a polyunsaturated
fatty acid sensor in mammals. PLoS ONE .
https://doi.org/10.1371/journal.pone.0038439
- Murphy, K. G., & Bloom, S. R. (2006). Gut hormones and the regulation
of energy homeostasis. Nature .
https://doi.org/10.1038/nature05484
- Nagata, K., Duggan, A., Kumar, G., & García-Añoveros, J. (2005).
Nociceptor and hair cell transducer properties of TRPA1, a channel for
pain and hearing. Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.0013-05.2005
- Nagatomo, K., & Kubo, Y. (2008). Caffeine activates mouse TRPA1
channels but suppresses human TRPA1 channels. Proceedings of the
National Academy of Sciences of the United States of America .
https://doi.org/10.1073/pnas.0809769105
- Nakajima, S., Hira, T., Yahagi, A., Nishiyama, C., Yamashita, T.,
Imagi, J., & Hara, H. (2014). Unsaturated aldehydes induce CCK
secretion via TRPA1 in STC-1 cells. Molecular Nutrition and Food
Research . https://doi.org/10.1002/mnfr.201300412
- Nassini, R., Pedretti, P., Moretto, N., Fusi, C., Carnini, C.,
Facchinetti, F., … Materazzi, S. (2012). Transient receptor
potential ankyrin 1 channel localized to non-neuronal airway cells
promotes non-neurogenic inflammation. PLoS ONE .
https://doi.org/10.1371/journal.pone.0042454
- Neto, J. G. O., Boechat, S. K., Romão, J. S., Pazos-Moura, C. C., &
Oliveira, K. J. (2020). Treatment with cinnamaldehyde reduces the
visceral adiposity and regulates lipid metabolism, autophagy and
endoplasmic reticulum stress in the liver of a rat model of early
obesity. Journal of Nutritional Biochemistry .
https://doi.org/10.1016/j.jnutbio.2019.108321
- Ng, M., Fleming, T., Robinson, M., Thomson, B., Graetz, N., Margono,
C., … Gakidou, E. (2014). Global, regional, and national
prevalence of overweight and obesity in children and adults during
1980-2013: A systematic analysis for the Global Burden of Disease
Study 2013. The Lancet .
https://doi.org/10.1016/S0140-6736(14)60460-8
- Nilius, B., Appendino, G., & Owsianik, G. (2012). The transient
receptor potential channel TRPA1: From gene to pathophysiology.Pflugers Archiv European Journal of Physiology .
https://doi.org/10.1007/s00424-012-1158-z
- Nilius, B., & Flockerzi, V. (2014). Mammalian transient receptor
potential (TRP) cation channels. Preface. Handbook of
Experimental Pharmacology .
- Nilius, B., & Owsianik, G. (2011). The transient receptor potential
family of ion channels. Genome Biology .
https://doi.org/10.1186/gb-2011-12-3-218
- Nilius, B., Prenen, J., & Owsianik, G. (2011). Irritating channels:
The case of TRPA1. Journal of Physiology .
https://doi.org/10.1113/jphysiol.2010.200717
- Nozawa, K., Kawabata-Shoda, E., Doihara, H., Kojima, R., Okada, H.,
Mochizuki, S., … Ito, H. (2009). TRPA1 regulates
gastrointestinal motility through serotonin release from
enterochromaffin cells. Proceedings of the National Academy of
Sciences of the United States of America .
https://doi.org/10.1073/pnas.0805323106
- Numazawa, S., Takase, M., Ahiko, T., Ishii, M., Shimizu, S. I., &
Yoshida, T. (2012). Possible involvement of transient receptor
potential channels in electrophile-induced insulin secretion from
RINm5F cells. Biological and Pharmaceutical Bulletin .
https://doi.org/10.1248/bpb.35.346
- Ohara, K., Fukuda, T., Ishida, Y., Takahashi, C., Ohya, R., Katayama,
M., … Nagai, K. (2017). β-Eudesmol, an oxygenized
sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous
system. Scientific Reports .
https://doi.org/10.1038/s41598-017-16150-6
- Oi-Kano, Y., Iwasaki, Y., Nakamura, T., Watanabe, T., Goto, T.,
Kawada, T., … Iwai, K. (2017). Oleuropein aglycone enhances
UCP1 expression in brown adipose tissue in high-fat-diet-induced obese
rats by activating β-adrenergic signaling. Journal of
Nutritional Biochemistry .
https://doi.org/10.1016/j.jnutbio.2016.11.009
- Okumura, Y., Narukawa, M., Iwasaki, Y., Ishikawa, A., Matsuda, H.,
Yoshikawa, M., & Watanabe, T. (2010). Activation of TRPV1 and TRPA1
by black pepper components. Bioscience, Biotechnology and
Biochemistry . https://doi.org/10.1271/bbb.90964
- Ortar, G., Morera, L., Schiano Moriello, A., Morera, E., Nalli, M., Di
Marzo, V., & De Petrocellis, L. (2012). Modulation of
thermo-transient receptor potential (thermo-TRP) channels by
thymol-based compounds. Bioorganic and Medicinal Chemistry
Letters . https://doi.org/10.1016/j.bmcl.2012.03.055
- Pappachan, J. M., Fernandez, C. J., & Chacko, E. C. (2019). Diabesity
and antidiabetic drugs. Molecular Aspects of Medicine .
https://doi.org/10.1016/j.mam.2018.10.004
- Park, M., Kim, K., Lee, Y. M., Rhyu, M. R., & Kim, H. Y. (2014).
Naringenin stimulates cholecystokinin secretion in STC-1 cells.Nutrition Research and Practice , 8 (2), 146–150.
https://doi.org/10.4162/nrp.2014.8.2.146
- Patil, M. J., Salas, M., Bialuhin, S., Boyd, J. T., Jeske, N. A., &
Akopian, A. N. (2020). Sensitization of small-diameter sensory neurons
is controlled by TRPV1 and TRPA1 association. FASEB Journal .
https://doi.org/10.1096/fj.201902026R
- Paulsen, C. E., Armache, J. P., Gao, Y., Cheng, Y., & Julius, D.
(2015a). Structure of the TRPA1 ion channel suggests regulatory
mechanisms. Nature . https://doi.org/10.1038/nature14367
- Paulsen, C. E., Armache, J. P., Gao, Y., Cheng, Y., & Julius, D.
(2015b). Structure of the TRPA1 ion channel suggests regulatory
mechanisms. Nature , 520 (7548), 511–517.
https://doi.org/10.1038/nature14367
- Peixoto-Neves, D., Soni, H., & Adebiyi, A. (2019). CGRPergic Nerve
TRPA1 Channels Contribute to Epigallocatechin Gallate-Induced
Neurogenic Vasodilation. ACS Chemical Neuroscience .
https://doi.org/10.1021/acschemneuro.8b00493
- Peyrot Des Gachons, C., Uchida, K., Bryant, B., Shima, A., Sperry, J.
B., Dankulich-Nagrudny, L., … Breslin, P. A. S. (2011). Unusual
pungency from extra-virgin olive oil is attributable to restricted
spatial expression of the receptor of oleocanthal. Journal of
Neuroscience . https://doi.org/10.1523/JNEUROSCI.1374-10.2011
- Pourmoradian, S., Mahdavi, R., Mobasseri, M., & Faramarzi, E. (2012).
Effects of Royal Jelly Supplementation on Body Weight and Dietary
Intake in Type 2 Diabetic Females, 2 (2), 231–235.
- Purhonen, A. K., Louhivuori, L. M., Kiehne, K., Åkerman, K. E. O., &
Herzig, K. H. (2008). TRPA1 channel activation induces cholecystokinin
release via extracellular calcium. FEBS Letters .
https://doi.org/10.1016/j.febslet.2007.12.005
- Renga, B., Mencarelli, A., Vavassori, P., Brancaleone, V., &
Fiorucci, S. (2010). The bile acid sensor FXR regulates insulin
transcription and secretion. Biochimica et Biophysica Acta -
Molecular Basis of Disease .
https://doi.org/10.1016/j.bbadis.2010.01.002
- Roden, M., Price, T. B., Perseghin, G., Petersen, K. F., Rothman, D.
L., Cline, G. W., & Shulman, G. I. (1996). Mechanism of free fatty
acid-induced insulin resistance in humans. Journal of Clinical
Investigation . https://doi.org/10.1172/JCI118742
- Rodgers, R. J., Tschöp, M. H., & Wilding, J. P. H. (2012).
Anti-obesity drugs: Past, present and future. DMM Disease Models
and Mechanisms . https://doi.org/10.1242/dmm.009621
- Saeedi, P., Petersohn, I., Salpea, P., Malanda, B., Karuranga, S.,
Unwin, N., … Williams, R. (2019). Global and regional diabetes
prevalence estimates for 2019 and projections for 2030 and 2045:
Results from the International Diabetes Federation Diabetes Atlas, 9th
edition. Diabetes Research and Clinical Practice , 157 ,
107843. https://doi.org/10.1016/j.diabres.2019.107843
- Sághy, É., Szoke, É., Payrits, M., Helyes, Z., Börzsei, R., Erostyák,
J., … Szolcsányi, J. (2015). Evidence for the role of lipid
rafts and sphingomyelin in Ca2+-gating of Transient Receptor Potential
channels in trigeminal sensory neurons and peripheral nerve terminals.Pharmacological Research , 100 , 101–116.
https://doi.org/10.1016/j.phrs.2015.07.028
- Sahin, N., Orhan, C., Erten, F., Tuzcu, M., Defo Deeh, P. B., Ozercan,
I. H., … Kazim, S. (2019). Effects of allyl isothiocyanate on
insulin resistance, oxidative stress status, and transcription factors
in high-fat diet/streptozotocin-induced type 2 diabetes mellitus in
rats. Journal of Biochemical and Molecular Toxicology ,33 (7), 1–9. https://doi.org/10.1002/jbt.22328
- Saini, V. (2010). Molecular mechanisms of insulin resistance in type 2
diabetes mellitus. World Journal of Diabetes .
https://doi.org/10.4239/wjd.v1.i3.68
- Salinari, S., Bertuzzi, A., Guidone, C., Previti, E., Rubino, F., &
Mingrone, G. (2013). Insulin sensitivity and secretion changes after
gastric bypass in normotolerant and diabetic obese subjects.Annals of Surgery . https://doi.org/10.1097/SLA.0b013e318269cf5c
- Samanta, A., Kiselar, J., Pumroy, R. A., Han, S., & Moiseenkova-Bell,
V. Y. (2018). Structural insights into the molecular mechanism of
mouse TRPA1 activation and inhibition. Journal of General
Physiology . https://doi.org/10.1085/jgp.201711876
- Sartorius, T., Peter, A., Schulz, N., Drescher, A., Bergheim, I.,
MacHann, J., … Hennige, A. M. (2014). Cinnamon extract improves
insulin sensitivity in the brain and lowers liver fat in mouse models
of obesity. PLoS ONE .
https://doi.org/10.1371/journal.pone.0092358
- Schmidt, M., Dubin, A. E., Petrus, M. J., Earley, T. J., &
Patapoutian, A. (2009). Nociceptive Signals Induce Trafficking of
TRPA1 to the Plasma Membrane. Neuron .
https://doi.org/10.1016/j.neuron.2009.09.030
- Schwarz, M. G., Namer, B., Reeh, P. W., & Fischer, M. J. M. (2017).
TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced
Pain. Journal of Pain .
https://doi.org/10.1016/j.jpain.2016.12.011
- Shigetomi, E., Jackson-Weaver, O., Huckstepp, R. T., O’Dell, T. J., &
Khakh, B. S. (2013). TRPA1 channels are regulators of astrocyte basal
calcium levels and long-term potentiation via constitutive d-serine
release. Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.5779-12.2013
- Shintaku, K., Uchida, K., Suzuki, Y., Zhou, Y., Fushiki, T., Watanabe,
T., … Tominaga, M. (2012). Activation of transient receptor
potential A1 by a non-pungent capsaicin-like compound, capsiate.British Journal of Pharmacology .
https://doi.org/10.1111/j.1476-5381.2011.01634.x
- Shokoohinia, Y., Chianese, G., Appendino, G., Di Marzo, V., De
Petrocellis, L., Ghannadi, A., … Taglialatela-Scafati, O.
(2013). Some like it pungent and vile. TRPA1 as a molecular target for
the malodorous vinyl disulfides from asafoetida. Fitoterapia ,90 , 247–251. https://doi.org/10.1016/j.fitote.2013.08.001
- Smith, M. P., Beacham, D., Ensor, E., & Koltzenburg, M. (2004).
Cold-sensitive, menthol-insensitive in the murine syphathetic nervous
system. NeuroReport .
https://doi.org/10.1097/01.wnr.0000126559.35631.54
- Sokabe, T., Tsujiuchi, S., Kadowaki, T., & Tominaga, M. (2008).
Drosophila painless is a Ca2+-requiring channel activated by noxious
heat. Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.2757-08.2008
- Solomon, T. P. J., & Blannin, A. K. (2009). Changes in glucose
tolerance and insulin sensitivity following 2 weeks of daily cinnamon
ingestion in healthy humans. European Journal of Applied
Physiology . https://doi.org/10.1007/s00421-009-0986-9
- Startek, J. B., Boonen, B., López-Requena, A., Talavera, A., Alpizar,
Y. A., Ghosh, D., … Talavera, K. (2019). Mouse TRPA1 function
and membrane localization are modulated by direct interactions with
cholesterol. ELife . https://doi.org/10.7554/eLife.46084
- Stepanyan, R. S., Indzhykulian, A. A., Catalinavélez-Ortega, A.,
Boger, E. T., Steyger, P. S., Friedman, T. B., & Frolenkov, G. I.
(2011). TRPA1-mediated accumulation of aminoglycosides in mouse
cochlear outer hair cells. JARO - Journal of the Association for
Research in Otolaryngology . https://doi.org/10.1007/s10162-011-0288-x
- Stokes, A., Wakano, C., Koblan-Huberson, M., Adra, C. N., Fleig, A.,
& Turner, H. (2006). TRPA1 is a substrate for de-ubiquitination by
the tumor suppressor CYLD. Cellular Signalling .
https://doi.org/10.1016/j.cellsig.2005.12.009
- Story, G. M., Peier, A. M., Reeve, A. J., Eid, S. R., Mosbacher, J.,
Hricik, T. R., … Patapoutian, A. (2003). ANKTM1, a TRP-like
channel expressed in nociceptive neurons, is activated by cold
temperatures. Cell .
https://doi.org/10.1016/S0092-8674(03)00158-2
- Sulak, M. A., Ghosh, M., Sinharoy, P., Andrei, S. R., & Damron, D. S.
(2018). Modulation of TRPA1 channel activity by Cdk5 in sensory
neurons. Channels , 12 (1), 65–75.
https://doi.org/10.1080/19336950.2018.1424282
- Sun, B., Bang, S. Il, & Jin, Y. H. (2009). Transient receptor
potential A1 increase glutamate release on brain stem neurons.NeuroReport . https://doi.org/10.1097/WNR.0b013e32832d2219
- Suo, Y., Wang, Z., Zubcevic, L., Hsu, A. L., He, Q., Borgnia, M. J.,
… Lee, S. Y. (2020). Structural Insights into Electrophile
Irritant Sensing by the Human TRPA1 Channel. Neuron ,105 (5), 882-894.e5.
https://doi.org/10.1016/j.neuron.2019.11.023
- Sura, L., Zíma, V., Marsakova, L., Hynkova, A., Barvík, I., &
Vlachova, V. (2012). C-terminal acidic cluster is involved in
Ca2+-induced regulation of human transient receptor potential ankyrin
1 channel. Journal of Biological Chemistry .
https://doi.org/10.1074/jbc.M112.341859
- T., K., A., K., Y., O., T., S., Y., H., N., C., … Y., K.
(2010). Activation of transient receptor potential A1 expressed in
intestinal epithelial cell increases intestinal blood flow via release
of adrenomedullin. Gastroenterology .
- Takaishi, M., Fujita, F., Uchida, K., Yamamoto, S., Shimizu, M. S.,
Uotsu, C. H., … Tominaga, M. (2012). 1,8-cineole, a TRPM8
agonist, is a novel natural antagonist of human TRPA1. Molecular
Pain . https://doi.org/10.1186/1744-8069-8-86
- Takayama, Y., Furue, H., & Tominaga, M. (2017).
4-isopropylcyclohexanol has potential analgesic effects through the
inhibition of anoctamin 1, TRPV1 and TRPA1 channel activities.Scientific Reports . https://doi.org/10.1038/srep43132
- Talavera, K., Gees, M., Karashima, Y., Meseguer, V. M., Vanoirbeek, J.
A. J., Damann, N., … Voets, T. (2009). Nicotine activates the
chemosensory cation channel TRPA1. Nature Neuroscience .
https://doi.org/10.1038/nn.2379
- Talavera, K., Startek, J. B., Alvarez-Collazo, J., Boonen, B.,
Alpizar, Y. A., Sanchez, A., … Nilius, B. (2020). Mammalian
Transient Receptor Potential TRPA1 Channels: From Structure to
Disease. Physiological Reviews .
https://doi.org/10.1152/physrev.00005.2019
- Tamura, Y., Iwasaki, Y., Narukawa, M., & Watanabe, T. (2012).
Ingestion of cinnamaldehyde, a TRPA1 agonist, reduces visceral fats in
mice fed a high-fat and high-sucrose diet. Journal of
Nutritional Science and Vitaminology .
https://doi.org/10.3177/jnsv.58.9
- Terada, Y., Hosono, T., Seki, T., Ariga, T., Ito, S., Narukawa, M., &
Watanabe, T. (2014). Sulphur-containing compounds of durian activate
the thermogenesis-inducing receptors TRPA1 and TRPV1. Food
Chemistry . https://doi.org/10.1016/j.foodchem.2014.02.031
- Terada, Y., Narukawa, M., & Watanabe, T. (2011). Specific hydroxy
fatty acids in Royal Jelly activate TRPA1. Journal of
Agricultural and Food Chemistry . https://doi.org/10.1021/jf1041646
- Terada, Y., Yamashita, R., Ihara, N., Yamazaki-Ito, T., Takahashi, Y.,
Masuda, H., … Watanabe, T. (2019). Human TRPA1 activation by
terpenes derived from the essential oil of daidai, Citrus aurantium L.
var. daidai Makino. Bioscience, Biotechnology and Biochemistry .
https://doi.org/10.1080/09168451.2019.1611405
- Tominaga, M., Momonaka, Y., Yokose, C., Tadaishi, M., Shimizu, M.,
Yamane, T., … Kobayashi-Hattori, K. (2016). Anorexic action of
deoxynivalenol in hypothalamus and intestine. Toxicon ,118 , 54–60. https://doi.org/10.1016/j.toxicon.2016.04.036
- Tremmel, M., Gerdtham, U. G., Nilsson, P. M., & Saha, S. (2017).
Economic burden of obesity: A systematic literature review.International Journal of Environmental Research and Public
Health . https://doi.org/10.3390/ijerph14040435
- Uchida, K., Miura, Y., Nagai, M., & Tominaga, M. (2012).
Isothiocyanates from Wasabia japonica activate transient receptor
potential ankyrin 1 channel. Chemical Senses .
https://doi.org/10.1093/chemse/bjs065
- Utreras, E., Futatsugi, A., Pareek, T. K., & Kulkarni, A. B. (2009).
Molecular roles of Cdk5 in pain signaling. Drug Discovery Today:
Therapeutic Strategies . https://doi.org/10.1016/j.ddstr.2009.04.004
- Valassi, E., Scacchi, M., & Cavagnini, F. (2008). Neuroendocrine
control of food intake. Nutrition, Metabolism and Cardiovascular
Diseases . https://doi.org/10.1016/j.numecd.2007.06.004
- Voolstra, O., & Huber, A. (2014). Post-Translational Modifications of
TRP Channels. Cells . https://doi.org/10.3390/cells3020258
- Wang, S., Kobayashi, K., Kogure, Y., Yamanaka, H., Yamamoto, S., Yagi,
H., … Dai, Y. (2018). Negative regulation of TRPA1 by AMPK in
primary sensory neurons as a potential mechanism of painful diabetic
neuropathy. Diabetes . https://doi.org/10.2337/db17-0503
- Wang, Y. Y., Chang, R. B., Waters, H. N., McKemy, D. D., & Liman, E.
R. (2008). The nociceptor ion channel TRPA1 is potentiated and
inactivated by permeating calcium ions. Journal of Biological
Chemistry . https://doi.org/10.1074/jbc.M803568200
- Wang, Z., Ye, D., Ye, J., Wang, M., Liu, J., Jiang, H., … Wan,
J. (2019). The TRPA1 channel in the cardiovascular system: Promising
features and challenges. Frontiers in Pharmacology .
https://doi.org/10.3389/fphar.2019.01253
- Watanabe, T., Sakurada, N., & Kobata, K. (2001). Capsaicin-,
resiniferatoxin-, and olvanil-induced adrenaline secretions in rats
via the vanilloid receptor. Bioscience, Biotechnology and
Biochemistry . https://doi.org/10.1271/bbb.65.2443
- Williams, R., Karuranga, S., Malanda, B., Saeedi, P., Basit, A.,
Besançon, S., … Colagiuri, S. (2020). Global and regional
estimates and projections of diabetes-related health expenditure:
Results from the International Diabetes Federation Diabetes Atlas, 9th
edition. Diabetes Research and Clinical Practice .
https://doi.org/10.1016/j.diabres.2020.108072
- Woll, K. A., Skinner, K. A., Gianti, E., Bhanu, N. V., Garcia, B. A.,
Carnevale, V., … Gaudet, R. (2017). Sites Contributing to TRPA1
Activation by the Anesthetic Propofol Identified by Photoaffinity
Labeling. Biophysical Journal .
https://doi.org/10.1016/j.bpj.2017.08.040
- Wu, J. L., Sweet, T. B., & Clapham, D. E. (2010). International Union
of Basic and Clinical Pharmacology. LXXVI. Current progress in the
Mammalian TRP ion channel family. Pharmacological Reviews .
https://doi.org/10.1124/pr.110.002725
- Wu, W., Zhou, H. R., Bursian, S. J., Link, J. E., & Pestka, J. J.
(2017). Calcium-sensing receptor and transient receptor ankyrin-1
mediate emesis induction by deoxynivalenol (vomitoxin).Toxicological Sciences . https://doi.org/10.1093/toxsci/kfw191
- Wu, W., Zhou, H. R., & Pestka, J. J. (2017). Potential roles for
calcium-sensing receptor (CaSR) and transient receptor potential
ankyrin-1 (TRPA1) in murine anorectic response to deoxynivalenol
(vomitoxin). Archives of Toxicology .
https://doi.org/10.1007/s00204-016-1687-x
- Xiao, B., Dubin, A. E., Bursulaya, B., Viswanath, V., Jegla, T. J., &
Patapoutian, A. (2008). Identification of transmembrane domain 5 as a
critical molecular determinant of menthol sensitivity in mammalian
TRPA1 channels. Journal of Neuroscience .
https://doi.org/10.1523/JNEUROSCI.2772-08.2008
- Xiao, B., & Patapoutian, A. (2011). Scratching the surface: A role of
pain-sensing TRPA1 in itch. Nature Neuroscience .
https://doi.org/10.1038/nn.2813
- Xu, H., Delling, M., Jun, J. C., & Clapham, D. E. (2006). Oregano,
thyme and clove-derived flavors and skin sensitizers activate specific
TRP channels. Nature Neuroscience .
https://doi.org/10.1038/nn1692
- YANG, M. Q., YE, L. L., LIU, X. L., QI, X. M., LV, J. Di, WANG, G.,
… ZHOU, X. H. (2016). Gingerol activates noxious cold ion
channel TRPA1 in gastrointestinal tract. Chinese Journal of
Natural Medicines . https://doi.org/10.1016/S1875-5364(16)30040-1
- Yokoyama, T., Ohbuchi, T., Saito, T., Sudo, Y., Fujihara, H., Minami,
K., … Ueta, Y. (2011). Allyl isothiocyanates and cinnamaldehyde
potentiate miniature excitatory postsynaptic inputs in the supraoptic
nucleus in rats. European Journal of Pharmacology .
https://doi.org/10.1016/j.ejphar.2011.01.011
- Yoneshiro, T., Kaede, R., Nagaya, K., Aoyama, J., Saito, M.,
Okamatsu-Ogura, Y., … Terao, A. (2018). Royal jelly ameliorates
diet-induced obesity and glucose intolerance by promoting brown
adipose tissue thermogenesis in mice. Obesity Research and
Clinical Practice , 12 (1), 127–137.
https://doi.org/10.1016/j.orcp.2016.12.006
- Zanotto, K. L., Merrill, A. W., Carstens, M. I., & Carstens, E.
(2007). Neurons in superficial trigeminal subnucleus caudalis
responsive to oral cooling, menthol, and other irritant stimuli.Journal of Neurophysiology .
https://doi.org/10.1152/jn.00996.2006
- Zhang, C., He, X., Sheng, Y., Xu, J., Yang, C., Zheng, S., …
Huang, K. (2020). Allicin Regulates Energy Homeostasis through Brown
Adipose Tissue. IScience , 23 (5), 101113.
https://doi.org/10.1016/j.isci.2020.101113
- Zhang, Z., Tóth, B., Szollosi, A., Chen, J., & Csanády, L. (2018).
Structure of a TRPM2 channel in complex with Ca2+ explains unique
gating regulation. ELife . https://doi.org/10.7554/elife.36409
- Zhao, J., Lin King, J. V., Paulsen, C. E., Cheng, Y., & Julius, D.
(2020). Irritant-evoked activation and calcium modulation of the TRPA1
receptor. Nature . https://doi.org/10.1038/s41586-020-2480-9
- Zhong, J., Pollastro, F., Prenen, J., Zhu, Z., Appendino, G., &
Nilius, B. (2011). Ligustilide: A novel TRPA1 modulator.Pflugers Archiv European Journal of Physiology .
https://doi.org/10.1007/s00424-011-1021-7
- Zhou, H. R., & Pestka, J. J. (2015). Deoxynivalenol
(vomitoxin)-induced cholecystokinin and glucagon-like peptide-1
release in the STC-1 enteroendocrine cell model is mediated by
calcium- sensing receptor and transient receptor potential ankyrin-1
channel. Toxicological Sciences , 145 (2), 407–417.
https://doi.org/10.1093/toxsci/kfv061
- Zimova, L., Barvikova, K., Macikova, L., Vyklicka, L., Sinica, V.,
Barvik, I., & Vlachova, V. (2020). Proximal C-Terminus Serves as a
Signaling Hub for TRPA1 Channel Regulation via Its Interacting
Molecules and Supramolecular Complexes. Frontiers in
Physiology . https://doi.org/10.3389/fphys.2020.00189
- Zuo, J., Zhao, D., Yu, N., Fang, X., Mu, Q., Ma, Y., … Gao, S.
(2017). Cinnamaldehyde Ameliorates Diet-Induced Obesity in Mice by
Inducing Browning of White Adipose Tissue. Cellular Physiology
and Biochemistry . https://doi.org/10.1159/000479268
- Zurborg, S., Yurgionas, B., Jira, J. A., Caspani, O., & Heppenstall,
P. A. (2007). Direct activation of the ion channel TRPA1 by Ca2+.Nature Neuroscience . https://doi.org/10.1038/nn1843
- Zygmunt, P. M., & Högesättt, E. D. (2014). TRPA1. Handbook of
Experimental Pharmacology .
https://doi.org/10.1007/978-3-642-54215-2_23