Author contribution:
H.H. conceived and coordinated the project. T.A.M., A.A.A. and A.M.K.
recruited the cohort. N.L., P.Z., and M.M.Y. performed the zebrafish
modeling. N.L. was in charge of the genetic analysis and bioinformatics
with aids of N.K., X.F.. N.L., A.M.K. and H.H. wrote the manuscript with
comments from all authors.