Other studies in clinical and laboratory findings
a metanalyses showed that the main clinical manifestations of COVID-19
were fever , cough , and dyspnea
(Jiang et al., 2020). in a study with 208 patients, median age was 50.5
years, 51.4% of them were men and 48.6% were women. 7.7% of the
patients had pulmonary diseases, 19.7%
hypertension, and 6.3% diabetes.
In our study, 26.5% of the patients had diabetes, hypertension and
Asthma. Among all symptoms, 70.2% and 55.3% were belonged to fever and
cough respectively. In compatible, 20.2% cases had decreased white
blood cell count, and 29.3% cases had declined
lymphocyte count. 74% of them had
elevated CRP, and 11.1% had elevated LDH in the present study (Zhang et
al., 2020b). In a retrospective cohort study, The mean age of the
patients were 59.5 years and 67% patients were male (Shi et al.,
2020).In a study, of 138 hospitalized patients, the median age was 56
years and 54.3% were men. Common symptoms were included fever 98.6%,
and dry cough 59.4%. Lymphopenia occurred in 70.3% patients. HRCT
showed bilateral patchy shadows or ground glass opacity in the lungs of
all patients (Wang et al., 2020).
In a Meta analysis study, including a total of 50404 patients with
2019-nCoV infection, the incidence of fever was 90.9% , and cough was
70.8%, moreover the incidence of
abnormal chest CT was 95.6%
(Sun et al., 2020), abnormal HRCT
in our study was 88%. In a study in Beijing of 262 patients, the median
age of patients was 47.5 and 48.5% of them were men. The most common
symptoms at the onset of illness were fever (82.1%), cough (45.8%),
dyspnea (6.9%) (Tian et al., 2020) that compatible with our study. In
the other study(Zhang et al., 2020a) of 140 hospitalized COVID‐19 cases,
a 1:1 ratio of men and women COVID-19 patients was found(50.7%), with a
median age of 57.0 . Fever (91.7%), cough (75.0%) were the most common
clinical manifestations, whereas
hypertension (30.0%) and diabetes
mellitus (12.1%) were the most
common comorbidities (Zhang et al., 2020a). Bilateral patchy opacity or
ground glass (89.6%) was the most common radiological finding.
Lymphopenia (75.4%) and eosinopenia (52.9%) were seen in most cases.
Eosinopenia with lymphopenia may be an indicator for diagnosis. Allergic
diseases, asthma, and COPD are not risk factors for SARS-CoV-2
infection (Zhang et al., 2020a).
The most common comorbidities in our study were hypertension, diabetes
mellitus and asthma. Also, bilateral multilobar patchy ground glass
opacities, bilateral multilobar patchy ground glass opacities and
bilateral alveolar consolidations were the most common radiological
findings in present study. Another study showed that of 1099 patients,
the median age of the patients was 47 years; 41.9% of the patients were
female. The common symptoms were fever and cough.
Ground-glass opacity was the most
common radiologic finding on chest CT (56.4%). 83.2% of the patients
had lymphocytopenia. Patients often presented without fever, and many
did not have abnormal radiologic findings(Guan et al., 2020).
Ground-glass opacity in present study was higher common finding. Similar
to our study, lymphocytopenia in COVID-19 patients was seen in the other
studies(Surveillances, 2020, Diao et al., 2020).In a metha analysis, for
656 patients, fever 88.7%, cough 57.6% and dyspnea 45.6% were the
most prevalent manifestations(Rodriguez-Morales et al., 2020).Of the 99
patients with 2019-nCoV pneumonia, The average age of the patients was
55·5 years, including 67 men and 32 women. 83% of the patients had
fever, 82% cough, 31% shortness of breath, and 11% myalgia. According
to imaging findings, 75% patients showed bilateral pneumonia, 14%
patients showed multiple mottling and ground-glass opacity, and 1%
patient had pneumothorax (Chen et al., 2020).Of the 10 cases, the
average age was 56.5 years , 60% of the patients were males, Dry cough
was the main symptom, followed by fever and fatigue. Chest computed
tomography results were nonspecific, mainly with ground-glass
attenuation and/or shadow images (Xia et al., 2020). Fever 72%, and
cough 83% were common symptoms in a study. 33% of them had an abnormal
chest radiograph finding or lung crepitations. Lymphopenia was present
in 39% (Young et al., 2020). A total of 5700 patients were included
with median age, 63 years, and 39.7% female. The most common
comorbidities were hypertension 56.6%, and diabetes 33.8% (Richardson
et al., 2020). In a study, The prevalence of asthma in patients with
COVID-19 was 0.9% (Li et al., 2020). During the course of a study 21
COVID-19 positive patients were admitted in , Jaipur, 66.66% of the
patients were men and 80.90% were less than 60 years of old. Almost
33.33% patients were asymptomatic and of those who were symptomatic,
cough was seen in 85.71% that followed by myalgia (64.28%), fever
(78.57%), and dyspnea (28.57%). 14.28 % of the cases had
co morbidities in the form of
diabetes mellitus, hypertension, hypothyroidism, or coronary artery
disease. moreover, 52.38% of the patients had lymphopenia(Bhandari et
al., 2020). These patterns in comorbidities and lymphopenia were seen in
our study, too.