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Characteristics of Children with Coronavirus Disease-2019 From The Pediatric Emergency Room
  • +7
  • emel berksoy,
  • Ali Kanik,
  • Alper Çiçek,
  • Şefika Bardak,
  • Gülşah Demir,
  • Pelin Elibol,
  • Nisel Yılmaz,
  • Tuğçe Çelik,
  • Gamze Gökalp,
  • Dilek Yilmaz Çiftdoğan
emel berksoy
Izmir Tepecik Training and Research Hospital
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Ali Kanik
Izmir Katip Celebi Universitesi
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Alper Çiçek
Izmir Tepecik Training and Research Hospital
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Şefika Bardak
Izmir Tepecik Training and Research Hospital
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Gülşah Demir
Izmir Tepecik Training and Research Hospital
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Pelin Elibol
Izmir Tepecik Training and Research Hospital
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Nisel Yılmaz
Izmir Tepecik Training and Research Hospital
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Tuğçe Çelik
Izmir Tepecik Training and Research Hospital
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Gamze Gökalp
Izmir Katip Celebi Universitesi
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Dilek Yilmaz Çiftdoğan
Izmir Katip Celebi Universitesi
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Abstract

We describe the demographic, clinical, and laboratory characteristics of children with COVID 19 in comparison with those of not-laboratory-confirmed cases. We conducted a cross-sectional study on the epidemiological, clinical, radiological, and laboratory characteristics, and outcome of 422 children (aged 0–18 years) with suspected and confirmed COVID 19 admitted to the pediatric emergency department from March 23rd to July 23rd, 2020. Of the 422 children with suspected COVID-19 included in this study, COVID-19 was PCR-confirmed in 78 (18.4%). Fever (51.2%) and cough (43.5%) were the most prominent symptoms in children with confirmed cases. The clinical status of the patients with confirmed COVID-19 was significantly milder than that of those with suspected COVID-19. The proportion of COVID-19 pneumonia cases was 44.4%, 5.5%, 18.7%, and 8.5% for the age groups of ≤ 1, 2–6, 7–12, and ≥ 12 years, respectively. Of the 422 children, 128 (30.3%) underwent nasopharyngeal PCR testing for other respiratory viral pathogens; 21 (16.4%) were infected with viral pathogens other than severe acute respiratory syndrome-related coronavirus-2. Only one patient (4.7%) with confirmed COVID-19 had coinfection with respiratory syncytial virus and rhinovirus. The areas under the receiver-operating characteristics curves were 0.812 for WBCs, 0.752 for neutrophils, 0.717 for lactate dehydrogenase, and 0.708 for lymphocyte for predicting COVID-19 (p ≤ 0.001). Fever and cough or other clinical symptoms or signs should not be considered hallmarks of COVID 19. In this study, the WBC, neutrophil, and lymphocyte counts were predictive of COVID-19 positivity.

Peer review status:ACCEPTED

28 Nov 2020Submitted to Pediatric Pulmonology
30 Nov 2020Submission Checks Completed
30 Nov 2020Assigned to Editor
01 Dec 2020Reviewer(s) Assigned
13 Jan 2021Review(s) Completed, Editorial Evaluation Pending
14 Jan 2021Editorial Decision: Revise Major
23 Feb 20211st Revision Received
24 Feb 2021Submission Checks Completed
24 Feb 2021Assigned to Editor
24 Feb 2021Reviewer(s) Assigned
11 Mar 2021Review(s) Completed, Editorial Evaluation Pending
14 Mar 2021Editorial Decision: Revise Minor
07 Apr 20212nd Revision Received
08 Apr 2021Assigned to Editor
08 Apr 2021Submission Checks Completed
08 Apr 2021Reviewer(s) Assigned
26 Apr 2021Review(s) Completed, Editorial Evaluation Pending
27 Apr 2021Editorial Decision: Revise Minor
14 May 20213rd Revision Received
17 May 2021Submission Checks Completed
17 May 2021Assigned to Editor
17 May 2021Reviewer(s) Assigned
16 Jun 2021Review(s) Completed, Editorial Evaluation Pending
17 Jun 2021Editorial Decision: Revise Minor
22 Jun 20214th Revision Received
22 Jun 2021Submission Checks Completed
22 Jun 2021Assigned to Editor
22 Jun 2021Reviewer(s) Assigned
07 Jul 2021Review(s) Completed, Editorial Evaluation Pending
09 Jul 2021Editorial Decision: Revise Minor
18 Jul 20215th Revision Received
20 Jul 2021Assigned to Editor
20 Jul 2021Reviewer(s) Assigned
20 Jul 2021Submission Checks Completed
05 Aug 2021Review(s) Completed, Editorial Evaluation Pending
08 Aug 2021Editorial Decision: Revise Minor
13 Aug 20216th Revision Received
14 Aug 2021Submission Checks Completed
14 Aug 2021Assigned to Editor
14 Aug 2021Reviewer(s) Assigned
14 Aug 2021Review(s) Completed, Editorial Evaluation Pending
20 Aug 2021Editorial Decision: Revise Minor
20 Aug 20217th Revision Received
23 Aug 2021Submission Checks Completed
23 Aug 2021Assigned to Editor
24 Aug 2021Review(s) Completed, Editorial Evaluation Pending
25 Aug 2021Editorial Decision: Accept