An interesting case of chronic myeloid leukemia (CML) with T315I
mutation raising suspicion of de novo AML, a diagnostic conundrum.
Chronic myeloid leukemia (CML) is a myeloproliferative disorder due to
translocation between chromosomes (9, 22), known as the “Philadelphia
chromosome.” In 2016, the World health organization (WHO) introduced a
new clinical entity of de novo acute myeloid leukemia (AML). Both
diseases share some commonalities, therefore, create a challenge to