Figure legends
Figure 1. Flowchart of this study
LPR, laryngopharyngeal reflux; MII, multichannel intraluminal impedance; PPI, proton pump inhibitor; RSI, reflux symptom index
Figure 2. Box plot showing differences in several proximal parameters of the 24-h multichannel intraluminal impedance (MII)-pH monitoring between non-responders and responders with laryngopharyngeal reflux (LPR). Responders showed a significantly higher proximal all reflux time and proximal longest reflux time compared to non-responders (p = 0.0040 and 0.0216, respectively; A, B). However, there were no significant differences in the proximal all reflux episodes between the two groups (p = 0.4781; C).
Figure 3. Receiver operating characteristic (ROC) curve analysis for determining the appropriate cut-off value of proximal all reflux time and proximal longest reflux time for predicting responders with laryngopharyngeal reflux (LPR). For proximal all reflux time, >0.000517% was the best cut-off value to predict responders with LPR (A). For proximal longest reflux time, >0.61 min was the best cut-off value to predict responders with LPR (B).
AUC, area under the ROC curve; CI, confidence interval; Sens., sensitivity; Spec., specificity