Abstract
Cardiotoxicity is a term that includes various undesirable
cardiovascular events during chemotherapy in hematological cancer
patients. Cardiotoxicity can occur both during chemotherapy and at
different times after its completion. Its manifestations are diverse, it
can proceed without symptoms and be registered only with instrumental
and laboratory research, or be accompanied by a severe, sometimes
life-threatening clinical picture. In clinical practice doctors,
oncohematologists often face the manifestation of cardiac arrhythmias
and its conduction disorders in patients. Acute drug toxicity may also
develop resulting in drug-induced cardiac arrhythmias. This case report
deals with a clinical case of a patient who underwent inpatient
treatment of the underlying disease acute leukemia. During the
treatment, multiple infectious complications arose. In the selection of
treatment for these complications, medications of various groups were
prescribed according to vital indications. This therapy, in turn,
unfortunately, led to the clinical death of the patient. The cause could
be drug-induced QT/QTc prolongation. A young man, who had no history of
structural heart disease, became acutely ill, and during the treatment
of the underlying disease (polychemotherapy) received side effects from
drug groups that led to the patient’s clinical death.