De-escalation Antibiotic Therapy Alleviates Organ Injury through Modulation of NET Formation during Sepsis
Short title: Antibiotic de-escalation to treat sepsis.
Tian Xie1#, MD; Chengnan Chu1#, MD; Shilong Sun1,PhD; Xinyu Wang1,PhD; Zehua Duan1,PhD; Weiwei Ding1,2, MD, PhD; Jieshou Li1, MD, PhD.
1 Division of Trauma and Surgical Intensive Care Unit, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, Jiangsu Province, P.R.China.
2 Division of Trauma and Surgical Intensive Care Unit, the First School of Clinical Medicine, Southern Medical University, Guangdong Province, P.R.China.
# These authors contributed equally to the work.
Correspondence author :
Weiwei Ding, MD, PhD;
Division of Trauma and Surgical Intensive Care Unit, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province; or the First School of Clinical Medicine, Southern Medical University, Guangdong Province, P.R.China;
TEL: +86-13851659525;
E-mail:dingwei_nju@hotmail.com