Introduction:
Since the outbreak of the coronavirus in early December 2019, in Wuhan, China, the virus has rapidly spread throughout the world, gaining a “Pandemic” status. Since then, studies, case reports, and research papers started to be published3,1 linking the virus to a myriad clinical manifestation, involving various systems. While the primary target of the virus is the respiratory system, the neurovascular invasiveness of the virus is demonstrated in humans and animals2,3. However, some neurological manifestations in COVID-19 patients are reported but still not well-understood.
Studies have shown that the most common neurological manifestations were nonspecific such as headache, dizziness, and agitation4,5. Other manifestations include stroke, seizures, and encephalopathy4,6. Cranial nerve involvement in COVID-19 patient apart from anosmia and ageusia is rare8,7.
We present here a case of isolated ophthamloparesis in a patient with a mild COVID-19 pneumonia and a comprehensive literature review of similar cases published in English from December 2019 to end of March 2021.