Figure Legends
Fig1 Venn diagrams for influenza target. Based on Drugbank ,GeneCard,
OMIM, TTD, PharmGkbdatabase, 229 influenza-related targets were found.
Fig2 Venn diagrams for the co-target between 242 targets of active
ingredients and 229 influenza-related targets. 31 key targets were
obtained after the duplicative terms deleted.
Fig3. Network diagram between active components and target genes. The
circle hexagon nodes represent the active components, the blue hexagon
nodes represent the target genes. Nodes size are proportional to their
degree.
Fig4. PPI network construction and analysis. PPI network of the
co-expressed genes. The PPI network was constructed via the Search Tool
for the Retrieval of Interacting Genes online, degree values of 11
target proteins are higher than the average for further analysis.
Fig5.Top 10 GO enrichments in BP,CC,MF (Fig 5) GO enrichment. X-axis is
enrichment gene ratio, Y-axis is biological process, molecular function
and cellular component analysis. Color represents the adjusted p-value,
the bluer the color, the smaller the adjusted p-value.
Fig6. KEGG pathway enrichment and top 30 KEGG pathways annotation. (Fig
6). X-axis is enrichment gene count, Y-axis is KEGG pathway, and the
color of bar chart represents the adjusted p-value.
Fig7.The docking complex of four targets and their strongest binding
components. the active site residues are shown. JUN(7A-7C). ILIB
(7D-7F).