Author contributions
YY, XZ, YZ, GD and YG conceptualised the study design. GD, LZ and ZZ collected demographic, clinical, and laboratory data. WG and XRZ plotted the figure and tables. GD, YG, LZ and ZZ wrote the first draft. XZ,YZ and YY commented on and revised the manuscript, WG, XZ, and TG analyzed the data. All authors read and approved the final report.