3.3.1. Basic characteristics
Among 462 patients with PIVSD, 47.2% had CS (95%CI: 0.267-0.676) patients, which results from 18 included articles (155/333). About 35.8% (95%CI: 0.114- 0.602) patients needed IABP and 49.4%(95%CI: 0.217- 0.772) needed inotropes,seventeen (192/325) and twelve (102/195) included studies were enrolled. Coronary single-vessel, double-vessel and triple-vessel disease were present in 48.9% (132/270), 34.8% (94/270), and 16.3% (44/270) of patients, respectively. Revascularization and Prior surgical closure rate was 39.4% (95%CI: 0.221- 0.568) and 80.9% (95%CI: 0.010- 0.355), respectively eighteen (119/331) and twenty-one(71/333) included articles were assessed for this outcome. The rate of primary closure at the acute phase reported in twenty-one studied (155/360) was 29.7% (95%CI: 0.095- 0.499). The weighted mean results were as follows: time from AMI to VSD and time to VSD closure was 2.6 days, 17.3 days. The defect size and device size were 13.1 mm and 19.6 mm. The clinical follow-up time was 589.8 days. Table 1 summarizes the initial assessment results of 27 studies.