Appendectomy | Appendectomy | Appendectomy | Appendectomy | Appendectomy | Appendectomy | Compared to Control | Compared to Control | |
Yes | Yes | Yes | No | No | No | |||
Variables
|
Events
|
PY
|
Rate#
|
Events
|
PY
|
Rate#
|
Crude HR (95% CI) | Adjusted HR† (95% CI) |
All | ||||||||
Follow-up time, years | ||||||||
<3 | 131 | 678513 | 19.3 | 31 | 685753 | 4.52 | 4.26(2.88, 6.31)*** | 3.99(2.69, 5.91)*** |
3-6 | 64 | 504262 | 12.7 | 22 | 512187 | 4.30 | 2.96(1.82, 4.80)*** | 2.67(1.64, 4.35)*** |
>6 | 60 | 555167 | 10.8 | 34 | 568921 | 5.98 | 1.81(1.19, 2.75)** | 1.74(1.14, 2.66)* |
Ulcerative colitis (UC) | ||||||||
Follow-up time, years | ||||||||
<3 | 54 | 7.96 | 15 | 2.19 | 3.63(2.05, 6.44)*** | 3.30(1.85, 5.88)*** | ||
3-6 | 32 | 6.35 | 11 | 2.15 | 2.96(1.49, 5.86)** | 2.67(1.34, 5.34)** | ||
>6 | 30 | 5.40 | 23 | 4.04 | 1.34(0.78, 2.30) | 1.28(0.74, 2.22) | ||
Crohn’s disease (CD) | ||||||||
Follow-up time, years | ||||||||
<3 | 77 | 11.4 | 16 | 2.33 | 4.85(2.83, 8.32)*** | 4.58(2.67, 7.87)*** | ||
3-6 | 32 | 6.35 | 11 | 2.15 | 2.95(1.49, 5.86)** | 2.65(1.33, 5.29)** | ||
>6 | 30 | 5.40 | 11 | 1.93 | 2.80(1.40, 5.58)** | 2.69(1.34, 5.40)** | ||
Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 | Rate#: Incidence rate per 10 000 person-years; Crude HR: relative hazard ratio; Adjusted HR†: adjusted hazard ratio after control for age, sex, and comorbidities of CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, and biliary stone; Comorbidity§: patients with CAD, hypertension, diabetes, hyperlipidemia, CVA, heart failure, COPD, CKD, alcohol-related diseases, cirrhosis, or biliary stone were classified as the comorbidity group. CAD, coronary artery disease; CI, confidence interval; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular disease; PY, person years; SD, standard deviation *P < .05, **P < .01, ***P < .001 |