5. Conclusions
Taken together, in this study, we gained sight into the biochemical mechanisms of OCD from the activity of the neopterin–BH4 pathway and changes in inflammatory and oxidative parameters. Circulating TGF-1β and BH4 levels were significantly lower in the OCD group compared to the healthy control group, whereas neopterin and NO levels were significantly higher. Based on these findings, we postulate that the levels of TGF-1β and NO and the activation of the neopterin–BH4 pathway may be involved in the pathophysiology of OCD. This study not only provides insight into the mechanisms underlying OCD but also presents novel opportunities for the design and development of more effective therapeutic strategies.