ABSTRACT
Aim of Study : The goal of this study was to evaluate
ischemia-modified albumin (IMA) as a novel marker of oxidative stress in
tuberculosis patients and to investigate changes occurring in patients.
Methods: Our study included 50 patients with active lung
tuberculosis and 48 healthy controls. Serum ischemia-modified albumin
was measured with automated spectrometric method and results were
compared statistically.
Results: We found that IMA levels were significantly higher in
pulmonary tuberculosis patients than in the control group. Albumin
levels were significantly lower in the patient group than in the control
group.
Conclusion: The results of our study showed that we can use
this parameter as a new oxidative stress marker in the pathogenesis of
pulmonary tuberculosis. Evaluation of IMA and albumin parameters in
patients with pulmonary tuberculosis may contribute significantly to the
evaluation of these patients.
Keywords : Tuberculosis, oxidative stress, ischemia-modified
albümin.