Aim:We report here our experience of using pegylated granulocyte colony stimulating factor (peg-GCSF) for peripheral blood stem cell (PBSC) mobilisation in children. Methods: A total of 9 children suffering from high-risk/relapsed solid tumors were mobilised with chemotherapy and peg-GCSF (100 microgram/kg single dose). Mean age was 7.7years (range 2-15 years). Results:The mean time from peg-GCSF administration to PBSC harvest was 9.7 days. Adequate stem cells (median dose 26.9 million/kg) could be harvested in all children by a single apheresis procedure. No major adverse events observed. Conclusion: It is feasible and safe to mobilise PBSC with peg-GCSF in children with cancer.