2 Native TFs regulation in inhibitory effect of stress in Yeast
In order to survive in a dynamic changing environment, yeast has evolved a relatively perfect defense machineries to counteract various environmental stresses under the force of natural selection. These natural mechanisms confer the engineered strains ability on maintain homeostasis in industrial productions process. Highly diverse stresses are transmitted through different response modules to ultimate effectors. Among them, the three most common types of high temperature, acetic acid, and oxidative stress wake up different types of TFs which are part of stress-sensing mechanism system and regulate metabolic networks in yeast.
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