Data Collection and Statistical Analysis
Data were collected and stored electronically, in accordance with HIPAA
and in a de-identified format, using a registry identification number as
an identifier. Data were analyzed using a statistical software package
(R 3.6.3) with the assistance from the Department of Pediatrics and
Biostatistics. Continuous variables were presented as median and
interquartile range (IQR) and categorical variables were presented as
frequency and percentage. EACA and TXA patients were compared using
Wilcoxon rank sum test for continuous variables and Chi-square test for
categorical variables. Ordinal logistic regression model was used to
find the transfusion factors that associate with intraoperative and
postoperative blood loss adjusting for age, weight, operative time,
surgical vault category (anterior / fronto-orbital advancement,
mid-posterior, or total), and syndromic status.