Conclusion and Perspectives
In conclusion, autophagy plays an indispensable role in the occurrence and development of endometriosis. TFEB, as a key regulator of autophagy, its upstream and downstream signal molecules have abnormal expression in endometriosis. Moreover, apoptosis can be inhibited by TFEB mediated autophagy induction. Therefore, TFEB may be an important regulatory point of abnormal autophagy levels in endometriosis. At present, the treatment of endometriosis is still limited to hormone and surgery. However, hormone therapy is easy to relapse, and there are many side effects. Moreover, not all women with endometriosis have a response to hormonal therapy, and surgery is an invasive treatment. Therefore, it is necessary to find a new treatment for endometriosis, Autophagy is a good perspective for us to understand endometriosis, TFEB may also become a potential target for the treatment of endometriosis.