Figure Legends
Figure 1. The flowchart of our prospective study
A total of 520 patients diagnosed with KD were initially screened for
participation in this study. Of these, patients who had received initial
IVIG treatment at other medical facilities (n=87), received IVIG
treatment within 10 days of fever onset (n=12), or cases where IVIG
treatment was initiated before blood sampling (n=17) were excluded.
Another 19 patients were excluded because of incomplete laboratory data
or lack of follow-up results. Finally, data from 385 patients were
analyzed. Of the 385 patients, 326 (84.7%) responded to initial IVIG
treatment, whereas 59 (15.3%) did not respond. Of the 59 patients with
initial IVIG resistance, 23 did not respond to repeated IVIG treatment
and received pulse intravenous methylprednisolone infusion. Then data
analysis and multivariate logistic regression analysis were performed in
these groups.
Figure 2. The receiver-operating characteristic (ROC) curve for
coagulation profiles in predicting initial and repeated IVIG resistance.
(A) ROC curve for coagulation profiles (PT, APTT, D-dimer, ATIII) in
predicting initial IVIG resistance. (B) ROC curve for ATIII in
predicting repeated IVIG resistance.
Supplemental material 1 . Comparison of coagulation profiles
between the groups of CALs and non-CALs group in KD
Supplemental material 2 . Clinical correlation between
univariate factors and coagulation profile in the KD subjects