Statistics
Data analyses were performed using SPSS version 21.0 (SPSS Inc. Chicago,
IL, USA). Quantitative data are presented as the medians with the 25th
and 75th percentiles in square brackets, while qualitative data are
expressed as the number or percentage as appropriate. A chi-squared test
and unpaired Student’s t-test or Mann–Whitney U test were used to
compare the demographic characteristics, clinical manifestations, and
laboratory data. Significant indicators from univariate analysis were
then subjected to multivariate logistic regression analysis to identify
independent predictors of IVIG resistance. Receiver operating
characteristic (ROC) curve analysis was used to evaluate the value of
coagulative biomarkers for predicting the development of initial and
repeated IVIG resistance. A P-value <0.05 was considered
statistically significant.