A component of this excess mortality may be attributable to the surgical intervention since the bone trauma and the preparation of the bone to apply the implant induce activation of the hemostatic system causing a thrombogenic process in the lung vessels, the adition of cytotoxic chemical methylmethacrylate monomer in the case of cemented fixation of the implants is another factor contributing to the circulatory disturbances in the lung\cite{Dahl_1997}.