Exercise provocation tests
Patients ingested the maximum desensitization dose and underwent either a free running or treadmill ergonometric stress test or a stepping exercise test after 30 minutes. The EPT was performed for at least 15 minutes, with a target heart rate of >180 beats/minute. Patients with negative EPT results were instructed to exercise after ingestion at home to confirm the negative result. Patients with positive EPT results underwent repeat EPTs after a period of time (usually about 2 years) according to the physicians’ and families’ discretions to check for remission.