Figure legends
Figure 1. Flowchart of the exercise provocation test for cow’s milk.
After slow oral immunotherapy (OIT) to cow’s milk, 43 patients underwent the first exercise provocation test (EPT). Of them, 20 patients’ results were negative. One negative patient experienced a convincing event of exercise-induced allergic reaction to desensitization (EIARD) at home. Ultimately, 21 and 22 patients were diagnosed as EIARD-positive and EIARD-negative, respectively. Seven patients underwent a second EPT, of which four tested negative.
Figure 2. Flowchart of the exercise provocation test for wheat.
After slow oral immunotherapy (OIT) to wheat, 31 patients underwent the first exercise provocation test (EPT). Of them, 14 patients’ results were negative. One negative patient experienced a convincing event of exercise-induced allergic reaction on desensitization (EIARD) at home. Finally, 15 and 16 patients were diagnosed as EIARD-positive and EIARD-negative, respectively. Six patients underwent a second EPT, and four of them tested negative.
Figure 3. Time course of the specific IgE detection in response to cow’s milk, wheat, and each component in the ImmunoCAP® system.
In the EIARD-positive and EIARD-negative groups, sIgE levels of cow’s milk, casein, wheat, and ω-5 gliadin measured after slow oral immunotherapy (OIT) were lower than those measured before the start of OIT.