Ethical Considerations
This study was conducted in accordance with the Declaration of Helsinki and was approved by the institutional ethical board of Aichi Children’s Health and Medical Center (No. 2017001). All EPTs were performed after obtaining written informed consent of the parents and informed consent of the patients, including the permission to use the results for this retrospective research. Slow OIT was also conducted after obtaining approval from the ethical board (No. 2012043 and 201427) and informed consent of the parents and patients.