HDAC-2 activity in lung tissue
Shown in Figure 5 and Table 1, the lungs of mice with long-term CS exposure had a greater reduction in HDAC-2 activity when compared to the lungs of the mice in the sham CS exposure group. ROF, PTX and THEO were able to partially restore HDAC-2 activity. The addition of TRI to any of the PDEIs, however, did not enhance the restoration of HDAC-2 activity (P > 0.05).