Statistical Analysis
Statistical analyses were performed using Graphpad Prism software 5.0
(GraphPad Software Inc., La Jolla, California). Data were first tested
for normal distribution. Parametric (such as ANOVA and post hocDunnett’s comparisons) and non-parametric (such as Kruskal-Wallis test)
statistics were applied where appropriate. Stepwise regression was
applied to the pooled data, exploring the variables which were relevant
to the decline of HDAC-2 activity. P < 0.05 was
regarded as statistically significant.