Correlations
Multiple stepwise regressions were applied to the pooled data when searching for factors that had a significant impact on HDAC-2 activity, where ROS, IL-8 and TNF-α were set as independent variables. Only ROS remained in the final equation (adjusted R2 = 0.29, P < 0.001), implying that a decline in HDAC-2 activity was related to an increase in ROS activity.