METHODS
This study was cross-sectional and observational. At the time of
admission, each patient underwent a clinical evaluation, which included
a routine physical examination, a 12-lead electrocardiogram (ECG),
echocardiographic evaluation and standard laboratory tests (blood count,
sodium, potassium, creatinine, glomerular filtration rate, HbA1c, hsTn,
creatine kinase myocardial bound [CK-MB], and copeptin levels) and a
GRACE 1.0 risk score calculation 11. High sensitive Tn
and CK-MB levels were reevaluated after six hours.
The study was carried out in a university hospital with a tertiary
cardiology center. Among patients who were admitted to the emergency
services clinic with complaints of chest pain or equivalent between
September 2018 and October 2019, 200 in total were diagnosed with UA and
underwent coronary angiography (CAG). These patients were included in
the study (see Figure 1). Patients with hsTn elevation (either at
admission or at the six-hour follow-up), STEMI, end stage renal failure
(GFR<15 ml/min/1.73 m2 or renal replacement treatment),
profound anemia (hemoglobin level <10 gr/dl for men,
hemoglobin level <8 gr/dl for women), sepsis, injury or major
surgery in past four weeks, active malignancy, pregnancy, or those who
were unwilling or unable to give informed consent were excluded.