METHODS
This study was cross-sectional and observational. At the time of admission, each patient underwent a clinical evaluation, which included a routine physical examination, a 12-lead electrocardiogram (ECG), echocardiographic evaluation and standard laboratory tests (blood count, sodium, potassium, creatinine, glomerular filtration rate, HbA1c, hsTn, creatine kinase myocardial bound [CK-MB], and copeptin levels) and a GRACE 1.0 risk score calculation 11. High sensitive Tn and CK-MB levels were reevaluated after six hours.
The study was carried out in a university hospital with a tertiary cardiology center. Among patients who were admitted to the emergency services clinic with complaints of chest pain or equivalent between September 2018 and October 2019, 200 in total were diagnosed with UA and underwent coronary angiography (CAG). These patients were included in the study (see Figure 1). Patients with hsTn elevation (either at admission or at the six-hour follow-up), STEMI, end stage renal failure (GFR<15 ml/min/1.73 m2 or renal replacement treatment), profound anemia (hemoglobin level <10 gr/dl for men, hemoglobin level <8 gr/dl for women), sepsis, injury or major surgery in past four weeks, active malignancy, pregnancy, or those who were unwilling or unable to give informed consent were excluded.