INTRODUCTION
Quantification of left ventricular size and function from
echocardiography is important in the diagnosis, prognosis, and
management of pediatric heart disease.1 With rapid
improvement in technology, three-dimensional echocardiography (3DE)
evaluation of left ventricular (LV) volume and function in pediatrics
compares favorably with magnetic resonance imaging (MRI)2-5. However, a multicenter trial to generate
normative 3DE z-scores in a large pediatric population would be
desirable for clinical use.
A multicenter trial would provide important information regarding 3DE LV
volumes and function in children of various ages and sizes. Such a
large-scale study would also allow for generation of normative data in
pediatric patients. Thus, the aim of this study is to establish normal
z-score values in this unique population using 3DE volumes and function
in a multicenter trial.