2.2.1 | Patients and controls
A group of 101 patients with confirmed IgE-dependent HVA were qualified to participate in the study. Subsequently, 6 persons were disqualified due to the presence of exclusion criteria.
The final study group of 45 women and 44 men, was then divided into two subgroups: I-II, including participants with a history of hypersensitivity reactions of maximum severity up to the second degree according to the Müller’s scale [11] and III-IV, consisting of patients who have experienced at least one grade III or IV reactions in the past.
9 women and 11 men were qualified for the control group. They were healthy and in a similar age range to the study group. They presented a negative history of allergic and non-allergic hypersensitivity reactions and did not meet the exclusion criteria.