2.2.1 | Patients and controls
A group of 101 patients with confirmed IgE-dependent HVA were qualified
to participate in the study. Subsequently, 6 persons were disqualified
due to the presence of exclusion criteria.
The final study group of 45 women and 44 men, was then divided into two
subgroups: I-II, including participants with a history of
hypersensitivity reactions of maximum severity up to the second degree
according to the Müller’s scale [11] and III-IV, consisting of
patients who have experienced at least one grade III or IV reactions in
the past.
9 women and 11 men were qualified for the control group. They were
healthy and in a similar age range to the study group. They presented a
negative history of allergic and non-allergic hypersensitivity reactions
and did not meet the exclusion criteria.