3.1 | Population characteristics
As shown in table 1 and 2, subgroups I-II included 8 patients with a history of the first-degree reaction and 31 patients after second-degree reactions. Subgroups III-IV included 33 patients after third-degree reactions and 17 patients after fourth-degree reactions, respectively.
No statistically significant differences were found between subgroups I-II, III-IV and the control group in terms of basic demographic, anthropometric and biochemical data. In the studied subgroups, IgE-dependent reaction to wasp venom was a more frequent cause of post-stinging reactions (84.62% in subgroups I-II and 80 % in subgroups III-IV, p = 0.98) than allergy to honey bee venom (15.38% in groups I-II and 20 % in groups III-IV, p = 0.49); however, these differences were statistically insignificant.