Epidemiological information
COVID-19 PCR test was positive in at least one of the family members in 140 (80%) patients. Up to seven people in a family have tested positive for COVID-19 PCR. The mean number of people who tested positive for COVID-19 PCR was 2.3 ± 1.4. At least one family member was hospitalized in 32 (18.3%) patients, 12 (6.9%) of them their mothers, 11 (6.3%) of them their fathers, 6 (3.4%) of them their grandparents and 3 (1.7%) of them their siblings.
One hundred and seven (61.1%) of the patients were infected by close contact with family members diagnosed with COVID-19, 35 (20%) of the patients were infected via close contact with non-family members diagnosed with COVID-19, 11 (6.3%) of the patients had a history of exposure in an epidemic area, including wedding hall, condolence house and shopping center and 23 (13.1%) of the patients with unknown source of infection (Table1). Of the family members that are the source of infection, 44 (41.1%) were mothers, 37 (34.6%) were fathers, 14 (13.1%) were grandparents, 12 (11.2%) were siblings
In half of the 68 patients whose source of infection was outside of family members, nobody had COVID-19 at home after them, but at least one person at home was infected with COVID-19 in the other half.
The mean age of patients whose source of infection was outside of family members and whose source of infection was family members was 12.7±4.9 and 9.3±5.3 respectively (p<0.001). At least one family member was hospitalized in 31 patients whose source of infection was family members and at least one family member was hospitalized in patients whose source of infection was outside of family members (p<0.001). The mean number of symptoms of patients whose source of infection was outside of family members and whose source of infection was family members was 4.5±3.4 and 3.3±2.4 respectively (p<0.014).
Laboratory information
Within 175 patients, 61 (34.8%) underwent laboratory testing. Among these patients, leucopenia (White Blood Count<4.5x109/L) in 11 (%18) patients, lymphocytopenia (lymphocyte count<1.2x109/L) in 12 (%19.7) patients, neutropenia (neutrophil count<1.5x109/L) in three (4.9%) patients and thrombocytopenia (platelet count<150x109/L) in five (8.2%) patients were detected. Furthermore increases in alanine aminotransferase (>45 U/L) in five patients (minimum 46 U/L, maximum 69 U/L) and increases in aspartate aminotransferase (>50 U/L) in three patients (minimum 94 U/L, maximum 115 U/L) were detected, while decreases in calcium (<8.5 mg/dL) in nine patients (minimum 6.7 mg/dL, maximum 8.4 mg/dL), decreases in sodium (<135 mEq/L) in 13 (21.3%) patients (minimum 129 mEq/L, maximum 134 mEq/L) and decreases in potassium (<3.5 mEq/L) in three patients (minimum 3 mEq/L, maximum 3.4 mEq/L) were detected.
Imaging information
Fifty-two patients were underwent chest X-ray. Lung findings were detected in 19 (36.5%) patients. It was unilateral localized increase in density in seven patients on the right lower zone, bilateral localized increase in density in six patients, unilateral mild bronchial thickening in five patients on the right zone and bilateral diffuse increase in density in one patient.