Data extraction:
Two independent authors (M.H and A.Gha) conducted data extraction and following information were extracted: the first author’s name, publication year, country where RCTs were conducted, sample size, study design, age range and/or mean, soy isoflavones and soy protein dose and source, intervention duration, placebo kind, subjects health status, changes in mean of CRP and its corresponding standard deviation. Any discrepancies in this stage also were resolved through consultation with third reviewer. We converted all CRP measurements to the same unit (mg/L). Studies which had more than one intervention or comparison group were included separately.