Clinical evidence linking allergy to risk of middle ear inflammation
Author Year
Type of article
N (mean age)
Methods
Relevant results
Association. (Level of evidence)
Byeon, 2019 (27)
Epidemiologic observational study
N=472 (9.6yr ± 0.4)
Survey data
Children with AR had twice significantly higher risk of OM.
Yes (Level IV) No distinction between AOM and OME
Martines et al. 2016 (28)
Case-control study
N=204 children and 204 controls
To investigate the main risk factors for AOM and OME and their prevalence in Sicilian children
Allergy and urban localization increased the risk of OM in children exposed to smoke, respectively of 166% and 277%.
Yes (Level III) No distinction between AOM and OME
Salah et al. 2013 (26)
Retrospective study
N=340 infants with RAOM
To analyze the risk factors that are likely to be responsible for RAOM in children.
Authors did not find a significant association between RAOM and allergy
None (Level IV) with RAOM
Hardani et al. 2020 (10)
Case-control study
N=625 children (6 months – 7 years)
To investigate the relationship between the incidence of otitis media (acute, chronic and with effusion) and risk factors.
Allergic rhinitis was identified as one of the most important risk factors.
Yes (No distinction between phenotypes)