RESULTS AND DISCUSSION
The details of the systematic search performed are shown in figure 1. In
total, our search yielded 3010 articles after duplicates removal. We
excluded 1169 articles due to time of publication and type of article,
then 1841 were finally screened. This resulted 20 publications included
in a qualitative analysis. We summarized in tables the included studies
per each phenotype classifying evidence using GRADE methodology. No
studies were included in a quantitative synthesis (meta-analysis).