Right ventricular remodeling:
RV function was impaired at baseline and improved after TMVI. In keeping with improved RVSWI, RVFAC increased from 28±7% before TMVI to 33±8% at hospital discharge (p=0.03), and 34±9% at 3-months (p<0.001 vs baseline) (Table 5; Figure 3b). TAPSE increased from 1.0±0.3cm before TMVI to 1.5±0.5cm at 3-months (p=0.03). RVFWLS improved from -14.2±5.0% before TMVI to -17.6±7.3% at 3-months (p=0.05), whilst there was a non-significant trend towards improved RVS’ (Table 5).
There was a significant reduction in RV length post TMVI (p=0.04) with an associated reduction in TR severity. At discharge, 41 (89%) patients had no detectable/trivial or mild TR (p<0.001), an improvement that was sustained at 3-month follow-up (Table 5; Figure 4). PASP decreased significantly (from 49±16mmHg to 36±12mmHg at 3-months; p<0.001) (Table 5; Figure 3c).