Hemodynamics.
In the present study, the low mean aortic valve gradient of 8.2±3.2 at
30-day, 10.2±4.1 mmHg at 1-year is consistent with previous reports of
the same valve 9. The study result is similar to the
1-month mean valve gradients of other valves (7.9±4.0 mmHg and 7.7±5.1
mmHg reported with the Jenevalve6 and Direct Flow
Medical valve 29), although the results provided
little information on the effects of the stent on AR hemodynamics. All
patients had mild or less PVL at 1-year in the study, with no patients
having moderate or severe PVL. These results compare favorably to a
recent study that residual moderate or severe aortic regurgitation rate
after the procedure was high as 9.2% in other studies24. Several characteristics include enhanced
positioning accuracy, controlled and anatomically correct implantation
and improved sealing even in eccentric annular calcifications. The low
rates of moderate to severe PVL might be a contributing factor in low
all-cause mortality rate at 1-year. However, with the low mortality rate
at 1-year compared to patients with AS, patients with AR were younger
and faced the risk of bioprosthetic valve deterioration and the need for
reintervention.