3.2 | Simulating the observed data with MetHis
Using MetHis , we produced 90,000 vectors of 24 summary statistics each, overall highly consistent with the observed ones for the ACB and the ASW populations respectively. First, each observed statistic is visually reasonably well simulated under the nine competing scenarios here considered (Supplementary Figure S7 ). Second, the observed data each fell into the simulated sets of 24 summary statistics projected in the first four PCA dimensions (Supplementary Figure S8 ). Finally, the observed summary statistics vectors were not significantly different (p-value = 0.468 and 0.710, for the ACB and ASW respectively) from the simulated ones using a goodness-of-fit approach (Supplementary Figure S9 ). Therefore, we successfully simulated datasets producing sets of summary statistics reasonably close to the observed ones, despite considering constant effective population sizes, fixed virtual source population genetic pool-sets, and neglecting mutation during the admixture process.