What’s new
This study is the first report of thiol-disulfide homeostasis in HCV-infected patients.
Thiol/disulfide homeostasis is disturbed and shifts to the disulfide side in patients with HCV infection.
TOS and OSI were higher and TAS was lower in HCV-infected patients compared to healthy controls.
This study shows that patients with HCV infection are vulnerable to oxidative stress and have disturbed status of oxidant- antioxidant.