Genetic loci- 9th chromosome |
Unknown |
Unknown |
PFR1 |
Perforin |
Cytolysis and immune regulation |
UNC13D |
MUNC13-4 |
Prime cytolytic granules |
STX11 |
Syntaxin |
Transport cytolytic granules |
STXBP |
Syntaxin binding protien |
Fuse cytolytic granules to cell
membrane, and release perforin |