2.1 Study Design
A retrospective cohort study was conducted in Children’s Health Ireland, Crumlin, the largest tertiary paediatric centre in Ireland. Children with DS aged 0-18 years and a confirmed diagnosis of OSA by polysomnography (PSG) who were commenced on NIV treatment were included in the study. Data from non-DS patients on NIV therapy attending our service were also collected for comparison. This study was approved by the hospital ethics committee.
Children attending our NIV services were identified via the downloadable data cloud platform (Fisher & Paykel, Auckland, NZ) data were available from March 2014 to August 2019. A total of 106 children met inclusion criteria.