Conclusions
This study analyzed the associations between polymorphisms and
haplotypes of sIL-2R, IL-10, IFN-γ, IRF5 , and CCR2 and
susceptibility to EBV-HLH in children. The IL2RA rs2104286 AA
genotype and A allele, IL-10 rs1800896 AA genotype and A allele,
and IL-10 rs1800872 CC genotype and C allele, as well as theIL2RA AGT and IL-10 ACC haplotypes were identified as
possible susceptibility risk factors for HLH in children with EBV.