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Caption for figures
FIGURE 1 Schematic framework of data searching and processing
FIGURE 2 Quantitative assessment of proteins interacting with histone H1 subtypes. On A, darkened bars shows a total number of proteins and brightened bars shows the number of proteins individual for a given subtype. On B, pairwise grouping of histone H1 subtypes based on the amount of common interacting proteins
FIGURE 3 Localization of histone H1 subtypes interacting proteins determined with the ComPPI database. Abundance of proteins was expressed as a ratio of their amount in a given cell compartment to the whole number of proteins interacting with a given histone H1 subtype
FIGURE 4 Functions of histone H1 subtypes interacting proteins derived from the SIFTER database. Abundance of proteins assigned to functional category was expressed as a ratio of their amount to the whole number of proteins interacting with a given histone H1 subtype
FIGURE 5 Interface residues of histone H1 subtypes and their interacting proteins predicted by BIPSPI method. In parentheses, an amino acid side chain propensity (subscript: c – charged, p – polar and h – hydrophobic) and its location in secondary structure (superscript: H – helix, NR – Non-Regular) is depicted. Underlined residues were predicted by DisEMBL tool as disordered
FIGURE 6 Features of histone H1 interacting proteins indicating on a shared and distinct characteristic of histone H1 subtypes. Similarities and distinctions between molecular function and biological process were juxtaposed based on proportions of proteins frequently associated with a given feature and having comparable networks properties (darkened circles) versus the proteins rarely and/or completely unrelated to a given feature and having unlike networks properties (lightened circles), details in the text