2.4 │ Determination of histone H1 subtypes interacting proteins GO terms
Protein characterization with respect to the GO annotations, i.e. biological process, cellular component and molecular function, was done with CELLO2GO (subCELlular LOcalization Prediction with Functional Gene Ontology Annotation) and a g:GOSt tool of g:Profiler. The CELLO2GO is a tool that use BLAST for search a similarity of protein query sequence to the sequences of proteins which GO categories are deposited in the UniProt database. 15 The g:GOSt perform functional analysis identifying a statistically significantly enriched GO annotations using g:SCS (Set Counts and Sizes) correction method.16