¹Translational Medicine Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada

²Department of Immunology, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

³Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria

⁴BioTechMed-Graz, Graz, Austria

⁵Karl Landsteiner University of Health Sciences, Krems, Austria

⁶Department of Internal Medicine 1, University Hospital St. Pölten, Karl Landsteiner Institute for Nephrology St. Pölten, St. Pölten, Austria

⁷Division of Pediatric Pulmonology, Allergology and Endocrinology, Department of Pediatric and Adolescent Medicine, Medical University of Vienna, Vienna, Austria

⁸Department of Pediatric and Adolescent Medicine, University Hospital St. Pölten, St Pölten, Austria

^† Contributed equally

^‡ Contributed equally