ABTRACT:
Congenital pulmonary airway malformation (CPAM), previously known as
congenital cystic adenomatoid malformation (CCAM), is a rare
developmental lung abnormality with the potential for malignant
transformation. Bronchioloalveolar carcinoma (BAC), pleuropulmonary
blastoma (PPB), rhabdomyomatous dysplasia/rhabdomyosarcoma (RMS) have
been associated with CPAM, but it generally occurs in older children and
adults. We report an unusual case of a 1-day-old male newborn who
underwent lobectomy for a cystic lung lesion, which was found to be a
mucinous BAC with K-ras mutation in a type 1 CPAM.