Introduction
The 2019 novel coronavirus, or severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that results in coronavirus disease 2019 (COVID-19), has been declared a pandemic and is severely affecting the public health worldwide. The epidemic geographically focused in the city of Wuhan, Hubei in mainland China during Jan to Mar 2020. With the sharp increase in the number of infections, the number of pregnant women and children with COVID-19 is also on the rise. The neonates born to mothers with COVID-19 were investigated in isolation ward, and some of them were identified with COVID-191. CT scan is the primary diagnostic method of COVID-19, with specific imaging findings1. Bedside lung ultrasound (LUS) examination is convenient and non-ionizing, and widely used in the assessment or monitoring of patients with infective pneumonia and dyspnea, especially for COVID-19 neonates. Lung ultrasound score (LUSS)2is capable of defining severe loss of aeration, which is helpful in semi-quantitative evaluation of neonatal COVID-19 pneumonia. However, the morbidity of COVID-19 in pediatric population was low. Our hospital was the only designated children hospital in Wuhan for treating COVID-19. In this single center pioneer study, we explored the ultrasonic features and severity of aeration loss of neonatal COVID-19 using bedside lung ultrasound score method.