Introduction
The 2019 novel coronavirus, or severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) that results in coronavirus disease 2019
(COVID-19), has been declared a pandemic and is severely affecting the
public health worldwide. The epidemic geographically focused in the city
of Wuhan, Hubei in mainland China during Jan to Mar 2020. With the sharp
increase in the number of infections, the number of pregnant women and
children with COVID-19 is also on the rise. The neonates born to mothers
with COVID-19 were investigated in isolation ward, and some of them were
identified with COVID-191. CT scan is the primary
diagnostic method of COVID-19, with specific imaging
findings1. Bedside lung ultrasound (LUS) examination
is convenient and non-ionizing, and widely used in the assessment or
monitoring of patients with infective pneumonia and dyspnea, especially
for COVID-19 neonates. Lung ultrasound score (LUSS)2is capable of defining severe loss of aeration, which is helpful in
semi-quantitative evaluation of neonatal COVID-19 pneumonia. However,
the morbidity of COVID-19 in pediatric population was low. Our hospital
was the only designated children hospital in Wuhan for treating
COVID-19. In this single center pioneer study, we explored the
ultrasonic features and severity of aeration loss of neonatal COVID-19
using bedside lung ultrasound score method.