Participants and eligibility
The trial Patients who presented
to the Peking Union Medical College Hospital between December 2018 and
September 2019 were screened by
gynecologists and anesthesiologists for recruitment into the trial.
Individuals 18–65 years of age
were eligible if they met the following criteria: (1) had had an
elective gynaecologic laparoscopic
surgery in the form of simple procedure (defined as cystectomy or
myomectomy or hysterectomies +/−bilateral salpingo-oophorectomy);
(2) were designated under ASA
classification I–II; and (3)
provided signed informed consent. The exclusion criteria included (1) a
preoperative albumin blood concentration < 30 g/L; (2) weight
loss > 10% during the 6 months preceding surgery; (3)
having undergone emergency surgery; (4) and manifesting nonsteroidal
anti-inflammatory drug (NSAID) contraindications that included peptic
ulcer, a history of allergic reactions to NSAIDs; and aspirin-induced
asthma.