Acknowledgements
This work was supported by grants PI-16/01292 and PI-19/1366 from the Carlos III Health Institute (Spain) and the European Regional Development Funds. A short stay of LMM at Dr. ZhengheWang’s lab, in Case Western Reserve University (Cleveland, USA), was supported by a travel fellowship of the European Association for Cancer Research. The authors would like to thank the families for taking part in the study. We would also like to acknowledge Dr. Zhenghe Wang for his collaboration, Paula Diaque, Isabel Diaz Millan and Durgadevi Ravillah for their technical assistance, and the Biobank of Hospital Clinico San Carlos (Madrid, Spain) for the FFPE blocks, sections and pathology records.