H&E-staining
Samples were embedded in tissue freezing medium (Leica Biosystems, Germany) and 7 μm sections were made using a CryoStar™ NX70 Kryostat (Thermo Fisher, USA). The resulting sections were stained with H&E according to standard protocols. For morphometric analysis, images were captured at 200× magnifications using a light DMI8-Microscope (Leica, Germany).