GRS moderating the risk of recurrent wheeze and asthma. Y-axis indicates prevalence of recurrent wheeze (age 2-5 years) or asthma (diagnosed by age 5), and x-axis indicates low/moderate/high GRS. a) The prevalence of recurrent wheeze increases with GRS. b) The prevalence of asthma increases with GRS. c) The prevalence of recurrent wheeze decreases among children who were breastfed until 12 months, particularly among those with low or moderate genetic risk. d) The prevalence of recurrent wheeze increases among children who are exposed increasing amounts of NO2 in the three months of life as well ase) during months 4-6, especially among those with moderate to high genetic risk.