Discussion
Progressive Hemifacial atrophy and segmental vitiligo are two distinct
disease entities which lies within the autoimmune spectrum of disease.
The cases of co-occurrence of Progressive hemifacial atrophy and
homolateral segmental vitiligo are characterized by an onset at younger
age, rapid progression followed by stabilization, and dermatomal
distribution.3,4,5,6,7,8,9,10 Segmental Vitiligo is an
acquired idiopathic condition of localized depigmentation in a
unilateral dermatomal distribution that result from progressive loss of
functional melanocytes.2 The pathogenesis of the
segmental vitiligo is unclear and various hypothesis have been put
forward including sympathetic nerve dysfunction and immune
patho-mechanism. Different causative factors have been postulated in
morphea such as immunological abnormalities, trauma neurological
abnormalities and infectious diseases.3,11 There was
no significant family history, history of trauma or infections preceding
the onset of skin lesion and no any other significant clinical physical
findings suggestive of other possible causes for Progressive Hemifacial
Atrophy and Segmental Vitiligo.