CD27+IgD+ B cell amounts correlate with clinical and immunological features in SLE patients
The associations of CD27+IgD+ B cell amounts with demographic and clinical characteristics were analyzed. As shown in Figures 2A–L and Table 3, WBC, platelet count and serum C3 levels were positively correlated with CD27+IgD+B cell amounts. Besides, CD27+IgD+B cell amounts showed negative correlations with serum creatinine levels, SLEDAI and anti-dsDNA. However, no associations of CD27+IgD+B cells with disease duration, ESR, serum C4 levels and serum IgA, IgG and IgM levels were found. The above findings indicated a numerical deficiency of CD27+IgD+B cells in SLE.