Conclusion
To our knowledge, this work is the first study reporting
H2S as a novel potential virulence determinant ofM. bovis isolated in Egypt. Due to the occurrence of
fluoroquinolone resistance in M. bovis as well as increased
resistance to other antibiotics, susceptibility testing of this pathogen
should be implemented as a routine procedure and as a part of the
diagnostic process. This study also draws attention on the increasing
number of drug-resistant M. bovis , in particular in Egypt asin
Europe and worldwide. The data obtained in the present study shows the
weak presence of the vsp gene and the conjunctive absence of theuvr C gene in all field isolates tested provides evidence that the
serological tests based on Vsp antigens and molecular identification
depending on the uvr C gene used for cattle is not appropriate for
testing samples recovered from camels. In addition, these potential
virulence factors could not be used as candidates for drug therapy and
vaccine design.