Individual Variability
Urine specimens were classified into urotypes, defined by the
predominant (>50% abundance) genus
present.2 If no genus reached 50% abundance, the
urotype was classified as ‘divese’. And a total of 27 urine specimens
had matching urotypes, while all other samples were diverse. The most
frequent urotype in both cohorts was Lactobacillus(M
group 29.4%, M/S group 22.6%). Two urotypes were present in both
cohorts (Lactobacillus and Streptococcus ). TheHaemophilus , Escherichia-Shigella , Enterococcus andSneathia urotypes were present only in the mild cohort, whereas
the Gardnerella urotype was present only in the
moderate/severe
cohort; however, these differences were not statistically significant at
our current sample size. The number of different bacterial genera in
each individual’s urinary microbiome ranged from 24 to 117 (mild range
24–86 genera per sample, moderate/severe range 30–117 genera per
sample).